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A small molecule inhibitor prevents gut bacterial genotoxin production.
Volpe, Matthew R; Velilla, José A; Daniel-Ivad, Martin; Yao, Jenny J; Stornetta, Alessia; Villalta, Peter W; Huang, Hsin-Che; Bachovchin, Daniel A; Balbo, Silvia; Gaudet, Rachelle; Balskus, Emily P.
Affiliation
  • Volpe MR; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Velilla JA; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA.
  • Daniel-Ivad M; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Yao JJ; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Stornetta A; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.
  • Villalta PW; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.
  • Huang HC; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, MN, USA.
  • Bachovchin DA; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Balbo S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Gaudet R; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.
  • Balskus EP; Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, MN, USA.
Nat Chem Biol ; 19(2): 159-167, 2023 02.
Article in En | MEDLINE | ID: mdl-36253549

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyketides / Gastrointestinal Microbiome Limits: Humans Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2023 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyketides / Gastrointestinal Microbiome Limits: Humans Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2023 Document type: Article Affiliation country: United States Country of publication: United States