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Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 Omicron variant in mice.
Scheaffer, Suzanne M; Lee, Diana; Whitener, Bradley; Ying, Baoling; Wu, Kai; Liang, Chieh-Yu; Jani, Hardik; Martin, Philippa; Amato, Nicholas J; Avena, Laura E; Berrueta, Daniela Montes; Schmidt, Stephen D; O'Dell, Sijy; Nasir, Arshan; Chuang, Gwo-Yu; Stewart-Jones, Guillaume; Koup, Richard A; Doria-Rose, Nicole A; Carfi, Andrea; Elbashir, Sayda M; Thackray, Larissa B; Edwards, Darin K; Diamond, Michael S.
Affiliation
  • Scheaffer SM; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
  • Lee D; Moderna, Inc., Cambridge, MA, USA.
  • Whitener B; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
  • Ying B; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
  • Wu K; Moderna, Inc., Cambridge, MA, USA.
  • Liang CY; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
  • Jani H; Moderna, Inc., Cambridge, MA, USA.
  • Martin P; Moderna, Inc., Cambridge, MA, USA.
  • Amato NJ; Moderna, Inc., Cambridge, MA, USA.
  • Avena LE; Moderna, Inc., Cambridge, MA, USA.
  • Berrueta DM; Moderna, Inc., Cambridge, MA, USA.
  • Schmidt SD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.
  • O'Dell S; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.
  • Nasir A; Moderna, Inc., Cambridge, MA, USA.
  • Chuang GY; Moderna, Inc., Cambridge, MA, USA.
  • Stewart-Jones G; Moderna, Inc., Cambridge, MA, USA.
  • Koup RA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.
  • Doria-Rose NA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.
  • Carfi A; Moderna, Inc., Cambridge, MA, USA.
  • Elbashir SM; Moderna, Inc., Cambridge, MA, USA. sayda.elbashir@modernatx.com.
  • Thackray LB; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA. lthackray@wustl.edu.
  • Edwards DK; Moderna, Inc., Cambridge, MA, USA. darin.edwards@modernatx.com.
  • Diamond MS; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA. mdiamond@wustl.edu.
Nat Med ; 29(1): 247-257, 2023 01.
Article in En | MEDLINE | ID: mdl-36265510
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Limits: Animals / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2023 Document type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Limits: Animals / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2023 Document type: Article Affiliation country: United States