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A lysine residue from an extracellular turret switches the ion preference in a Cav3 T-Type channel from calcium to sodium ions.
Guan, Wendy; Orellana, Kaidy G; Stephens, Robert F; Zhorov, Boris S; Spafford, J David.
Affiliation
  • Guan W; Department of Biology, University of Waterloo, Waterloo, Ontario, Canada.
  • Orellana KG; Department of Biology, University of Waterloo, Waterloo, Ontario, Canada.
  • Stephens RF; Department of Biology, University of Waterloo, Waterloo, Ontario, Canada.
  • Zhorov BS; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada; Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia; Almazov National Medical Research Centre, St. Petersburg, Russia.
  • Spafford JD; Department of Biology, University of Waterloo, Waterloo, Ontario, Canada. Electronic address: david.spafford@uwaterloo.ca.
J Biol Chem ; 298(12): 102621, 2022 12.
Article in En | MEDLINE | ID: mdl-36272643
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sodium / Calcium / Calcium Channels, T-Type / Lysine Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Biol Chem Year: 2022 Document type: Article Affiliation country: Canada
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sodium / Calcium / Calcium Channels, T-Type / Lysine Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Biol Chem Year: 2022 Document type: Article Affiliation country: Canada