[The applications and challenges of liquid chromatography tandem mass spectrometry in maternal and child health].
Zhonghua Yu Fang Yi Xue Za Zhi
; 56(10): 1520-1526, 2022 Oct 06.
Article
in Zh
| MEDLINE
| ID: mdl-36274624
ABSTRACT
Due to its ultra-high sensitivity, specificity and throughput, liquid chromatography tandem mass spectrometry (LC-MS/MS) has become an important analytical tool in clinical laboratories in quantifying various small molecules, such as vitamins, bile acids, steroids and other internal metabolites relevant to maternal diseases. As an effective means of screening and diagnosing diseases in preventive medicine, LC-MS/MS has been widely used in maternal and child health, contributing to the reduction of the incidence of maternal and child diseases and premature morbidity and mortality. At present, LC-MS/MS is an emerging and powerful platform in laboratory testing in China, facing both challenges and opportunities. In this article, the representative applications in the field of maternal and child health are summarized and discussed, along with the major hurdles of LC-MS/MS in clinical recognition and implementation.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Child Health
/
Tandem Mass Spectrometry
Limits:
Child
/
Humans
Language:
Zh
Journal:
Zhonghua Yu Fang Yi Xue Za Zhi
Year:
2022
Document type:
Article
Affiliation country:
China