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MRI Outcomes Achieved by Simple Flow Blockage Technique in Symptomatic Carotid Artery Stenosis Stenting.
Hak, Jean-François; Arquizan, Caroline; Cagnazzo, Federico; Mahmoudi, Mehdi; Collemiche, Francois-Louis; Gascou, Gregory; Lefevre, Pierre-Henry; Derraz, Imad; Labreuche, Julien; Mourand, Isabelle; Gaillard, Nicolas; Corti, Lucas; Charif, Mahmoud; Costalat, Vincent; Dargazanli, Cyril.
Affiliation
  • Hak JF; Neuroradiology Department, CHRU Gui de Chauliac, Montpellier University Medical Center, 34295 Montpellier, France.
  • Arquizan C; LIIE, Aix Marseille University, 13005 Marseille, France.
  • Cagnazzo F; CERIMED, Aix Marseille University, 13005 Marseille, France.
  • Mahmoudi M; Neurology Department, CHRU Gui de Chauliac, Montpellier University Medical Center, 34295 Montpellier, France.
  • Collemiche FL; Neuroradiology Department, CHRU Gui de Chauliac, Montpellier University Medical Center, 34295 Montpellier, France.
  • Gascou G; Neuroradiology Department, CHRU Gui de Chauliac, Montpellier University Medical Center, 34295 Montpellier, France.
  • Lefevre PH; Neuroradiology Department, CHRU Gui de Chauliac, Montpellier University Medical Center, 34295 Montpellier, France.
  • Derraz I; Neuroradiology Department, CHRU Gui de Chauliac, Montpellier University Medical Center, 34295 Montpellier, France.
  • Labreuche J; Neuroradiology Department, CHRU Gui de Chauliac, Montpellier University Medical Center, 34295 Montpellier, France.
  • Mourand I; Neuroradiology Department, CHRU Gui de Chauliac, Montpellier University Medical Center, 34295 Montpellier, France.
  • Gaillard N; Biostatistics Department, Centre Hospitalier Universitaire Lille, 59000 Lille, France.
  • Corti L; Neurology Department, CHRU Gui de Chauliac, Montpellier University Medical Center, 34295 Montpellier, France.
  • Charif M; Neurology Department, CHRU Gui de Chauliac, Montpellier University Medical Center, 34295 Montpellier, France.
  • Costalat V; Neurology Department, CHRU Gui de Chauliac, Montpellier University Medical Center, 34295 Montpellier, France.
  • Dargazanli C; Neurology Department, CHRU Gui de Chauliac, Montpellier University Medical Center, 34295 Montpellier, France.
J Pers Med ; 12(10)2022 Sep 23.
Article in En | MEDLINE | ID: mdl-36294703
In this study, we aimed to determine the frequency and clinical impact of new ischemic lesions detected with diffusion-weighted-imaging-MRI (DWI-MRI) as well as the clinical outcomes after carotid artery stenting (CAS) using the simple flow blockage technique (SFB). This is a retrospective study with data extraction from a monocentric prospective clinical registry (from 2017 to 2019) of consecutive patients admitted for symptomatic cervical ICA stenosis or web. Herein, patients benefited from DWI-MRI before and within 48 h of CAS for symptomatic ICA stenosis or web. The primary endpoint was the frequency of new DWI-MRI ischemic lesions and the secondary (composite) endpoint was the rate of mortality, symptomatic stroke or acute coronary syndrome within 30 days of the procedure. All of the 82 CAS procedures were successfully performed. Among the 33 patients (40.2%) with new DWI-MRI ischemic lesions, 30 patients were asymptomatic (90.9%). Irregular carotid plaque surface with (n = 13, 44.8%) or without ulceration (n = 12, 60.0%) was associated with higher rates of new DWI-MRI lesions by comparison to patients with a regular plaque (n = 7, 25%) (p = 0.048) using the univariate analysis. Less than half of this CAS cohort using the SFB technique had new ischemic lesions detected with DWI-MRI. Among these patients, more than 90% were asymptomatic. Irregularity of the plaque seems to increase the risk of peri-procedural DWI-MRI lesions.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies / Observational_studies / Risk_factors_studies Language: En Journal: J Pers Med Year: 2022 Document type: Article Affiliation country: France Country of publication: Switzerland

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies / Observational_studies / Risk_factors_studies Language: En Journal: J Pers Med Year: 2022 Document type: Article Affiliation country: France Country of publication: Switzerland