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Performance Verification of CYP2C19 Enzyme Abundance Polymorphism Settings within the Simcyp Simulator v21.
Sychterz, Caroline; Gardner, Iain; Chiang, Manting; Rachumallu, Ramakrishna; Neuhoff, Sibylle; Perera, Vidya; Merali, Samira; Schmidt, Brian J; Gaohua, Lu.
Affiliation
  • Sychterz C; Clinical Pharmacology & Pharmacometrics, Bristol Myers Squibb, Lawrenceville, NJ 08540, USA.
  • Gardner I; Certara UK Ltd., Simcyp Division, Sheffield S1 2BJ, UK.
  • Chiang M; Clinical Pharmacology & Pharmacometrics, Bristol Myers Squibb, Lawrenceville, NJ 08540, USA.
  • Rachumallu R; Certara UK Ltd., Simcyp Division, Sheffield S1 2BJ, UK.
  • Neuhoff S; Certara UK Ltd., Simcyp Division, Sheffield S1 2BJ, UK.
  • Perera V; Clinical Pharmacology & Pharmacometrics, Bristol Myers Squibb, Lawrenceville, NJ 08540, USA.
  • Merali S; Clinical Pharmacology & Pharmacometrics, Bristol Myers Squibb, Lawrenceville, NJ 08540, USA.
  • Schmidt BJ; Clinical Pharmacology & Pharmacometrics, Bristol Myers Squibb, Lawrenceville, NJ 08540, USA.
  • Gaohua L; Clinical Pharmacology & Pharmacometrics, Bristol Myers Squibb, Lawrenceville, NJ 08540, USA.
Metabolites ; 12(10)2022 Oct 20.
Article in En | MEDLINE | ID: mdl-36295903
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: Metabolites Year: 2022 Document type: Article Affiliation country: United States Country of publication: Switzerland
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: Metabolites Year: 2022 Document type: Article Affiliation country: United States Country of publication: Switzerland