P/N-Heteroleptic Cu(I)-Photosensitizer-Catalyzed [3 + 2] Regiospecific Annulation of Aminocyclopropanes and Functionalized Alkynes.
J Org Chem
; 87(22): 15571-15581, 2022 11 18.
Article
in En
| MEDLINE
| ID: mdl-36322051
ABSTRACT
We report here a regiospecific [3 + 2] annulation between aminocyclopropanes and various functionalized alkynes enabled by a P/N-heteroleptic Cu(I) photosensitizer under photoredox catalysis conditions. Thus, a divergent construction of 3-aminocyclopentene derivatives including methylsulfonyl-, arylsulfonyl-, chloro-, ester-, and trifluoromethyl-functionalized aminocyclopentenes could be achieved with advantages of high regioselectivity, broad substrate compatibility, and mild and environmentally benign reaction conditions.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Photosensitizing Agents
/
Alkynes
Language:
En
Journal:
J Org Chem
Year:
2022
Document type:
Article