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Adverse Events Associated With Treatment for Pan-Susceptible Tuberculosis in San Francisco.
Louie, Janice K; Keh, Chris; Agraz-Lara, Rocio; Phillips, Allison; Graves, Susannah.
Affiliation
  • Louie JK; Division of Population Health, San Francisco Department of Public Health, San Francisco, California, USA.
  • Keh C; Department of Medicine, University of California-San Francisco, San Francisco, California, USA.
  • Agraz-Lara R; Department of Medicine, University of California-San Francisco, San Francisco, California, USA.
  • Phillips A; Division of Population Health, San Francisco Department of Public Health, San Francisco, California, USA.
  • Graves S; Division of Population Health, San Francisco Department of Public Health, San Francisco, California, USA.
Clin Infect Dis ; 76(6): 1121-1124, 2023 03 21.
Article in En | MEDLINE | ID: mdl-36322073
ABSTRACT
Of 373 patients treated for drug-susceptible tuberculosis, 35.4% (46.2% aged ≥65 years) developed moderate/severe adverse events that required treatment interruption (34.8%), first-line drug discontinuation (26.2%, primarily pyrazinamide), second-line drug initiation (30.0%), and treatment duration up to 3.8 months longer. More safe and effective options are needed, including for the elderly.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tuberculosis / Tuberculosis, Multidrug-Resistant Type of study: Risk_factors_studies Limits: Aged / Humans Country/Region as subject: America do norte Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2023 Document type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tuberculosis / Tuberculosis, Multidrug-Resistant Type of study: Risk_factors_studies Limits: Aged / Humans Country/Region as subject: America do norte Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2023 Document type: Article Affiliation country: United States