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Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features.
Robbe, Pauline; Ridout, Kate E; Vavoulis, Dimitrios V; Dréau, Helene; Kinnersley, Ben; Denny, Nicholas; Chubb, Daniel; Appleby, Niamh; Cutts, Anthony; Cornish, Alex J; Lopez-Pascua, Laura; Clifford, Ruth; Burns, Adam; Stamatopoulos, Basile; Cabes, Maite; Alsolami, Reem; Antoniou, Pavlos; Oates, Melanie; Cavalieri, Doriane; Gibson, Jane; Prabhu, Anika V; Schwessinger, Ron; Jennings, Daisy; James, Terena; Maheswari, Uma; Duran-Ferrer, Martí; Carninci, Piero; Knight, Samantha J L; Månsson, Robert; Hughes, Jim; Davies, James; Ross, Mark; Bentley, David; Strefford, Jonathan C; Devereux, Stephen; Pettitt, Andrew R; Hillmen, Peter; Caulfield, Mark J; Houlston, Richard S; Martín-Subero, José I; Schuh, Anna.
Affiliation
  • Robbe P; Department of Oncology, University of Oxford, Oxford, UK.
  • Ridout KE; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
  • Vavoulis DV; Department of Oncology, University of Oxford, Oxford, UK.
  • Dréau H; Department of Oncology, University of Oxford, Oxford, UK.
  • Kinnersley B; Department of Oncology, University of Oxford, Oxford, UK.
  • Denny N; Division of Genetics and Epidemiology, The Institute of Cancer Research, Sutton, UK.
  • Chubb D; Department of Medicine, Medical Research Council Molecular Haematology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Appleby N; Division of Genetics and Epidemiology, The Institute of Cancer Research, Sutton, UK.
  • Cutts A; Department of Oncology, University of Oxford, Oxford, UK.
  • Cornish AJ; Department of Oncology, University of Oxford, Oxford, UK.
  • Lopez-Pascua L; Division of Genetics and Epidemiology, The Institute of Cancer Research, Sutton, UK.
  • Clifford R; UK Health Security Agency, London, UK.
  • Burns A; Department of Haematology, University Hospital Limerick, Limerick, Ireland.
  • Stamatopoulos B; Limerick Digital Cancer Research Centre, School of Medicine,University of Limerick, Limerick, Ireland.
  • Cabes M; Department of Oncology, University of Oxford, Oxford, UK.
  • Alsolami R; Laboratory of Clinical Cell Therapy, Jules Bordet Institute, ULB Cancer Research Center (U-CRC)- Université Libre de Bruxelles (ULB), Brussels, Belgium.
  • Antoniou P; Oxford Molecular Diagnostics Centre, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, UK.
  • Oates M; Department of Medical Laboratory Technology, King Abdulaziz University, Jeddah, Saudi Arabia.
  • Cavalieri D; Illumina Cambridge Ltd., Cambridge, UK.
  • Schwessinger R; Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Jennings D; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
  • James T; Department of Medicine, Medical Research Council Molecular Haematology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Maheswari U; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
  • Duran-Ferrer M; Illumina Cambridge Ltd., Cambridge, UK.
  • Carninci P; Illumina Cambridge Ltd., Cambridge, UK.
  • Knight SJL; Biomedical Epigenomics Group, Institut d'Investigacions Biomédiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
  • Månsson R; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
  • Hughes J; Human Technopole, Milan, Italy.
  • Davies J; Oxford University Clinical Academic Graduate School, University of Oxford Medical Sciences Division, University of Oxford, John Radcliffe Hospital, Oxford, UK.
  • Ross M; Center for Hematology and Regenerative Medicine Huddinge, Karolinska Institute, Stockholm, Sweden.
  • Bentley D; Department of Medicine, Medical Research Council Molecular Haematology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Strefford JC; Department of Medicine, Medical Research Council Molecular Haematology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Devereux S; Illumina Cambridge Ltd., Cambridge, UK.
  • Pettitt AR; Illumina Cambridge Ltd., Cambridge, UK.
  • Hillmen P; Cancer Genomics, Cancer Sciences, Faculty of Medicine, Group University of Southampton, Southampton, UK.
  • Caulfield MJ; King's College Hospital, NHS Foundation Trust, London, UK.
  • Houlston RS; Kings College London, London, UK.
  • Martín-Subero JI; Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK.
  • Schuh A; Clatterbridge Cancer Centre NHS Foundation Trust, Liverpool, UK.
Nat Genet ; 54(11): 1675-1689, 2022 11.
Article in En | MEDLINE | ID: mdl-36333502
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2022 Document type: Article Affiliation country: United kingdom Country of publication: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2022 Document type: Article Affiliation country: United kingdom Country of publication: United States