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MicroRNAs' Crucial Role in Salivary Gland Cancers' Onset and Prognosis.
Bocchetti, Marco; Grisolia, Piera; Melisi, Federica; Ferraro, Maria Grazia; De Luca, Pietro; Camaioni, Angelo; Falco, Michela; Abate, Marianna; Misso, Gabriella; Alfano, Roberto; Accardo, Nunzio; Oliva, Flavia; Cossu, Alessia Maria; Caraglia, Michele; Scrima, Marianna; Ricciardiello, Filippo.
Affiliation
  • Bocchetti M; Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio, 7, 80138 Naples, Italy.
  • Grisolia P; Laboratory of Precision and Molecular Oncology, Biogem Scarl, Institute of Genetic Research, Contrada Camporeale, 83031 Ariano Irpino, Italy.
  • Melisi F; Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio, 7, 80138 Naples, Italy.
  • Ferraro MG; Laboratory of Precision and Molecular Oncology, Biogem Scarl, Institute of Genetic Research, Contrada Camporeale, 83031 Ariano Irpino, Italy.
  • De Luca P; Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio, 7, 80138 Naples, Italy.
  • Camaioni A; Laboratory of Precision and Molecular Oncology, Biogem Scarl, Institute of Genetic Research, Contrada Camporeale, 83031 Ariano Irpino, Italy.
  • Falco M; Department of Pharmacy, School of Medicine and Surgery, University of Naples "Federico II", Via D. Montesano 49, 80131 Naples, Italy.
  • Abate M; College of Medical, Veterinary and Life Sciences, School of Infection and Immunity, University of Glasgow, Glasgow G12 8TA, UK.
  • Misso G; Department of Medicine, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Baronissi, Italy.
  • Alfano R; Otolaryngology Department, San Giovanni-Addolorata Hospital, Via dell'Amba Aradam, 8, 00184 Rome, Italy.
  • Accardo N; Otolaryngology Department, San Giovanni-Addolorata Hospital, Via dell'Amba Aradam, 8, 00184 Rome, Italy.
  • Oliva F; Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio, 7, 80138 Naples, Italy.
  • Cossu AM; Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio, 7, 80138 Naples, Italy.
  • Caraglia M; Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio, 7, 80138 Naples, Italy.
  • Scrima M; Department of Advanced Medical and Surgical Sciences "DAMSS", University of Campania "Luigi Vanvitelli", Via S.M. di Costantinopoli 104, 80138 Naples, Italy.
  • Ricciardiello F; Ear Nose Throt Departement AORN Cardarelli, 80100 Napoli, Italy.
Cancers (Basel) ; 14(21)2022 Oct 28.
Article in En | MEDLINE | ID: mdl-36358723
ABSTRACT
Salivary gland cancer (SGC) is an uncommon and heterogeneous disease that accounts for around 8.5% of all head and neck cancers. MicroRNAs (miRNAs) consist of a class of highly conserved, short, single-stranded segments (18-25 nucleotides) of noncoding RNA that represent key gene-transcription regulators in physiological and pathological human conditions. However, their role in SGC development and progression is not completely clear. This review aims to compile and summarize the recent findings on the topic, focusing on the prognostic and diagnostic value of the major modulated and validated microRNAs in SGC. Their differential expression could possibly aid the clinician in delivering an early diagnosis, therapeutic strategy and precision medicine.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies / Screening_studies Language: En Journal: Cancers (Basel) Year: 2022 Document type: Article Affiliation country: Italy
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies / Screening_studies Language: En Journal: Cancers (Basel) Year: 2022 Document type: Article Affiliation country: Italy