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Empagliflozin Induced Ketosis, Upregulated IGF-1/Insulin Receptors and the Canonical Insulin Signaling Pathway in Neurons, and Decreased the Excitatory Neurotransmitter Glutamate in the Brain of Non-Diabetics.
Avgerinos, Konstantinos I; Mullins, Roger J; Vreones, Michael; Mustapic, Maja; Chen, Qinghua; Melvin, Denise; Kapogiannis, Dimitrios; Egan, Josephine M.
Affiliation
  • Avgerinos KI; Laboratory of Clinical Investigation, Intramural Program, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Mullins RJ; Laboratory of Clinical Investigation, Intramural Program, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Vreones M; Laboratory of Clinical Investigation, Intramural Program, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Mustapic M; Laboratory of Clinical Investigation, Intramural Program, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Chen Q; Laboratory of Clinical Investigation, Intramural Program, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Melvin D; Laboratory of Clinical Investigation, Intramural Program, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Kapogiannis D; Laboratory of Clinical Investigation, Intramural Program, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Egan JM; Laboratory of Clinical Investigation, Intramural Program, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
Cells ; 11(21)2022 10 25.
Article in En | MEDLINE | ID: mdl-36359767

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus, Type 2 / Alzheimer Disease / Sodium-Glucose Transporter 2 Inhibitors / Ketosis Limits: Female / Humans / Middle aged Language: En Journal: Cells Year: 2022 Document type: Article Affiliation country: United States Country of publication: Switzerland

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus, Type 2 / Alzheimer Disease / Sodium-Glucose Transporter 2 Inhibitors / Ketosis Limits: Female / Humans / Middle aged Language: En Journal: Cells Year: 2022 Document type: Article Affiliation country: United States Country of publication: Switzerland