Specific antibody deficiency to pneumococcal polysaccharide in a young adult with recurrent respiratory infections: a case report.
Monaldi Arch Chest Dis
; 93(3)2022 Nov 16.
Article
in En
| MEDLINE
| ID: mdl-36382810
ABSTRACT
Specific antibody deficiency against pneumococcal serotypes was detected in a patient with recurrent episodes of fever. A 21-year-old man presented with a two-month history of recurrent episodes of fever and shaking chills. He was diagnosed with recurrent episodes of pneumonia caused by Streptococcus pneumoniae serotype 19A and treated with amoxicillin. Serotype-specific antibodies were not produced against most of the serotypes, which were consistent with moderate specific antibody deficiency. After pneumococcal 13-valent conjugate vaccination and pneumococcal polysaccharide vaccination, he adequately responded to the infecting serotype with an antibody titer of 1.1 µg/mL. There were eventually no recurrent episodes of fever with pneumonia.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pneumonia
/
Streptococcus pneumoniae
Limits:
Adult
/
Humans
/
Male
Language:
En
Journal:
Monaldi Arch Chest Dis
Year:
2022
Document type:
Article