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The RTS,S malaria vaccine: Current impact and foundation for the future.
Beeson, James G; Kurtovic, Liriye; Valim, Clarissa; Asante, Kwaku Poku; Boyle, Michelle J; Mathanga, Don; Dobano, Carlota; Moncunill, Gemma.
Affiliation
  • Beeson JG; Burnet Institute, Melbourne 3004, Victoria, Australia.
  • Kurtovic L; Department of Infectious Diseases, University of Melbourne, Victoria, Australia.
  • Valim C; Monash University, Central Clinical School and Department of Microbiology, Victoria, Australia.
  • Asante KP; Burnet Institute, Melbourne 3004, Victoria, Australia.
  • Boyle MJ; Monash University, Central Clinical School and Department of Microbiology, Victoria, Australia.
  • Mathanga D; Department of Global Health, Boston University School of Public Health, Boston, MA, USA.
  • Dobano C; Kintampo Health Research Centre, Kintampo North Municipality, Bono East Region, Ghana.
  • Moncunill G; QIMR Berghofer Institute, Herston, Queensland, Australia.
Sci Transl Med ; 14(671): eabo6646, 2022 11 16.
Article in En | MEDLINE | ID: mdl-36383682
ABSTRACT
The RTS,S vaccine has recently been recommended for implementation as a childhood vaccine in regions with moderate-to-high malaria transmission. We discuss mechanisms of vaccine protection and longevity, implementation considerations, and future research needed to increase the vaccine's health impact, including vaccine modifications for higher efficacy and longevity of protection.
Subject(s)
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Malaria, Falciparum / Malaria Vaccines / Malaria Limits: Child / Humans / Infant Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2022 Document type: Article Affiliation country: Australia
Fulltext
Add to My VHL
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XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Malaria, Falciparum / Malaria Vaccines / Malaria Limits: Child / Humans / Infant Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2022 Document type: Article Affiliation country: Australia