Evaluating the utility of the Threshold of Toxicological Concern (TTC) and its exclusions in the biocompatibility assessment of extractable chemical substances from medical devices.

Patlewicz, Grace; Nelms, Mark; Rua, Diego

Patlewicz, Grace; Nelms, Mark; Rua, Diego.

Affiliation

Patlewicz G; Center for Computational Toxicology & Exposure (CCTE), U.S. Environmental Protection Agency, Research Triangle Park, Durham, NC 27709, USA.
Nelms M; Center for Computational Toxicology & Exposure (CCTE), U.S. Environmental Protection Agency, Research Triangle Park, Durham, NC 27709, USA.
Rua D; Oak Ridge Institute for Science and Education, Oak Ridge, TN 37830, USA.

Comput Toxicol ; 24: 1-11, 2022 Nov.

Article in En | MEDLINE | ID: mdl-36405647

Key words

Exclusions; Extractables; Medical devices; Threshold of Toxicological Concern (TTC); Toxtree

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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Comput Toxicol Year: 2022 Document type: Article Affiliation country: United States Country of publication: Netherlands

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