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Bcl11b and Atoh8 Coordinate Cellular Plasticity for Reprogramming and Transformation.
Huang, Mo-Fan; Shoemaker, Rachel; Lee, Dung-Fang.
Affiliation
  • Huang MF; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
  • Shoemaker R; UTHealth Houston Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Lee DF; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Cell Reprogram ; 24(6): 324-326, 2022 12.
Article in En | MEDLINE | ID: mdl-36409720
ABSTRACT
By dissecting and comparing the transcriptional trajectories and epigenomic traits of reprogramming and transforming cells at the single-cell resolution, Huyghe et al discovered Bcl11b and Atoh8, two key transcription factors controlling cell plasticity during pluripotent reprogramming and oncogenic transformation.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Cell Plasticity Limits: Humans Language: En Journal: Cell Reprogram Year: 2022 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Cell Plasticity Limits: Humans Language: En Journal: Cell Reprogram Year: 2022 Document type: Article Affiliation country: United States