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A diminished hydrophobic effect inside the GroEL/ES cavity contributes to protein substrate destabilization.
Korobko, Ilia; Eberle, Robin Benjamin; Roy, Mousam; Horovitz, Amnon.
Affiliation
  • Korobko I; Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Eberle RB; Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Roy M; Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Horovitz A; Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot 7610001, Israel.
Proc Natl Acad Sci U S A ; 119(48): e2213170119, 2022 11 29.
Article in En | MEDLINE | ID: mdl-36409898
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Folding / Chaperonin 60 Type of study: Prognostic_studies Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Document type: Article Affiliation country: Israel Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Folding / Chaperonin 60 Type of study: Prognostic_studies Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Document type: Article Affiliation country: Israel Country of publication: United States