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Suppressing gain-of-function proteins via CRISPR/Cas9 system in SCA1 cells.
Pappadà, Mariangela; Bonuccelli, Ottavia; Buratto, Mattia; Fontana, Riccardo; Sicurella, Mariaconcetta; Caproni, Anna; Fuselli, Silvia; Benazzo, Andrea; Bertorelli, Roberto; De Sanctis, Veronica; Cavallerio, Paolo; Simioni, Valentina; Tugnoli, Valeria; Salvatori, Francesca; Marconi, Peggy.
Affiliation
  • Pappadà M; Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, via Fossato di Mortara 64/B, 44121, Ferrara, Italy.
  • Bonuccelli O; Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, via Fossato di Mortara 64/B, 44121, Ferrara, Italy.
  • Buratto M; Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, via Fossato di Mortara 64/B, 44121, Ferrara, Italy.
  • Fontana R; Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, via Fossato di Mortara 64/B, 44121, Ferrara, Italy.
  • Sicurella M; Department of Life Sciences and Biotechnology, University of Ferrara, via L. Borsari 46, 44121, Ferrara, Italy.
  • Caproni A; Department of Environmental Sciences and Prevention, University of Ferrara, via L. Borsari 46, 44121, Ferrara, Italy.
  • Fuselli S; Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, via Fossato di Mortara 64/B, 44121, Ferrara, Italy.
  • Benazzo A; Department of Life Sciences and Biotechnology, University of Ferrara, via L. Borsari 46, 44121, Ferrara, Italy.
  • Bertorelli R; Department of Life Sciences and Biotechnology, University of Ferrara, via L. Borsari 46, 44121, Ferrara, Italy.
  • De Sanctis V; Next Generation Sequencing Core Facility, Department of Cellular, Computational and Integrative Biology-CIBIO, University of Trento, via Sommarive 9, 38123, Povo, Trento, Italy.
  • Cavallerio P; Next Generation Sequencing Core Facility, Department of Cellular, Computational and Integrative Biology-CIBIO, University of Trento, via Sommarive 9, 38123, Povo, Trento, Italy.
  • Simioni V; Next Generation Sequencing Core Facility, Department of Cellular, Computational and Integrative Biology-CIBIO, University of Trento, via Sommarive 9, 38123, Povo, Trento, Italy.
  • Tugnoli V; Division of Neurology, Department of Neuroscience and Rehabilitation, University Hospital of Ferrara, via A. Moro 8, 44100, Ferrara, Cona, Italy.
  • Salvatori F; Division of Neurology, Department of Neuroscience and Rehabilitation, University Hospital of Ferrara, via A. Moro 8, 44100, Ferrara, Cona, Italy.
  • Marconi P; Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, via Fossato di Mortara 64/B, 44121, Ferrara, Italy. francesca.salvatori@unife.it.
Sci Rep ; 12(1): 20285, 2022 11 24.
Article in En | MEDLINE | ID: mdl-36434031
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinocerebellar Ataxias Limits: Animals Country/Region as subject: Europa Language: En Journal: Sci Rep Year: 2022 Document type: Article Affiliation country: Italy Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinocerebellar Ataxias Limits: Animals Country/Region as subject: Europa Language: En Journal: Sci Rep Year: 2022 Document type: Article Affiliation country: Italy Country of publication: United kingdom