Iron Oxide Nanoparticles Decorated with Functional Peptides for a Targeted siRNA Delivery to Glioma Cells.

Chung, Seokhwan; Sugimoto, Yutaro; Huang, Jianxi; Zhang, Miqin

Chung, Seokhwan; Sugimoto, Yutaro; Huang, Jianxi; Zhang, Miqin.

ACS Appl Mater Interfaces ; 15(1): 106-119, 2023 Jan 11.

Article in En | MEDLINE | ID: mdl-36442077

Subject(s)

Brain Neoplasms; Glioma; Humans; Dacarbazine/pharmacology; Dacarbazine/therapeutic use; RNA, Small Interfering/pharmacology; Cell Line, Tumor; Glioma/drug therapy; Glioma/genetics; Temozolomide/pharmacology; Temozolomide/therapeutic use; Brain Neoplasms/drug therapy; Brain Neoplasms/genetics; O(6)-Methylguanine-DNA Methyltransferase/genetics; O(6)-Methylguanine-DNA Methyltransferase/metabolism; O(6)-Methylguanine-DNA Methyltransferase/pharmacology; Peptides/pharmacology; Magnetic Iron Oxide Nanoparticles; Antineoplastic Agents, Alkylating/pharmacology; Antineoplastic Agents, Alkylating/therapeutic use; Drug Resistance, Neoplasm

Key words

cell-penetrating peptide; chlorotoxin; functional peptide; glioma; iron oxide nanoparticle; siRNA

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Glioma Limits: Humans Language: En Journal: ACS Appl Mater Interfaces Journal subject: BIOTECNOLOGIA / ENGENHARIA BIOMEDICA Year: 2023 Document type: Article Country of publication: United States

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