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Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants.
Aragam, Krishna G; Jiang, Tao; Goel, Anuj; Kanoni, Stavroula; Wolford, Brooke N; Atri, Deepak S; Weeks, Elle M; Wang, Minxian; Hindy, George; Zhou, Wei; Grace, Christopher; Roselli, Carolina; Marston, Nicholas A; Kamanu, Frederick K; Surakka, Ida; Venegas, Loreto Muñoz; Sherliker, Paul; Koyama, Satoshi; Ishigaki, Kazuyoshi; Åsvold, Bjørn O; Brown, Michael R; Brumpton, Ben; de Vries, Paul S; Giannakopoulou, Olga; Giardoglou, Panagiota; Gudbjartsson, Daniel F; Güldener, Ulrich; Haider, Syed M Ijlal; Helgadottir, Anna; Ibrahim, Maysson; Kastrati, Adnan; Kessler, Thorsten; Kyriakou, Theodosios; Konopka, Tomasz; Li, Ling; Ma, Lijiang; Meitinger, Thomas; Mucha, Sören; Munz, Matthias; Murgia, Federico; Nielsen, Jonas B; Nöthen, Markus M; Pang, Shichao; Reinberger, Tobias; Schnitzler, Gavin; Smedley, Damian; Thorleifsson, Gudmar; von Scheidt, Moritz; Ulirsch, Jacob C; Arnar, David O.
Affiliation
  • Aragam KG; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA. karagam@broadinstitute.org.
  • Jiang T; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA. karagam@broadinstitute.org.
  • Goel A; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA. karagam@broadinstitute.org.
  • Kanoni S; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. karagam@broadinstitute.org.
  • Wolford BN; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Atri DS; Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, Oxford, UK.
  • Weeks EM; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Wang M; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Hindy G; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
  • Zhou W; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Grace C; Divisions of Cardiovascular Medicine and Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Roselli C; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Marston NA; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Kamanu FK; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Surakka I; Department of Population Medicine, Qatar University College of Medicine, Doha, Qatar.
  • Venegas LM; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Sherliker P; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
  • Koyama S; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.
  • Ishigaki K; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Åsvold BO; Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, Oxford, UK.
  • Brown MR; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Brumpton B; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • de Vries PS; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Giannakopoulou O; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Giardoglou P; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, USA.
  • Gudbjartsson DF; Institute for Cardiogenetics, University of Lübeck, Lübeck, Germany.
  • Güldener U; German Research Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Lübeck/Kiel, Lübeck, Germany.
  • Haider SMI; Medical Research Council Population Health Research Unit, CTSU-Nuffield Department of Population Health, Medical Sciences Division, University of Oxford, Oxford, UK.
  • Helgadottir A; Laboratory for Cardiovascular Genomics and Informatics, RIKEN Center for Integrative Medical Sciences, Tsurumi-ku, Yokohama, Japan.
  • Ibrahim M; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Tsurumi-ku, Yokohama, Japan.
  • Kastrati A; Department of Public Health and Nursing, K.G. Jebsen Center for Genetic Epidemiology, Norwegian University of Science and Technology, NTNU, Trondheim, Norway.
  • Kessler T; HUNT Research Centre, Norwegian University of Science and Technology, Levanger, Norway.
  • Kyriakou T; Department of Endocrinology, Clinic of Medicine, St. Olavs Hospital, Trondheim, Norway.
  • Konopka T; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Li L; Department of Public Health and Nursing, K.G. Jebsen Center for Genetic Epidemiology, Norwegian University of Science and Technology, NTNU, Trondheim, Norway.
  • Ma L; HUNT Research Centre, Norwegian University of Science and Technology, Levanger, Norway.
  • Meitinger T; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Mucha S; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Munz M; Department of Nutrition-Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
  • Murgia F; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
  • Nielsen JB; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
  • Nöthen MM; German Heart Centre Munich, Department of Cardiology, Technical University of Munich, Munich, Germany.
  • Pang S; Institute for Cardiogenetics, University of Lübeck, Lübeck, Germany.
  • Reinberger T; German Research Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Lübeck/Kiel, Lübeck, Germany.
  • Schnitzler G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
  • Smedley D; CTSU-Nuffield Department of Population Health, Medical Sciences Division, University of Oxford, Oxford, UK.
  • Thorleifsson G; German Heart Centre Munich, Department of Cardiology, Technical University of Munich, Munich, Germany.
  • von Scheidt M; German Research Center for Cardiovascular Research (DZHK e.V.), Partner Site Munich Heart Alliance, Munich, Germany.
  • Ulirsch JC; German Heart Centre Munich, Department of Cardiology, Technical University of Munich, Munich, Germany.
  • Arnar DO; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Nat Genet ; 54(12): 1803-1815, 2022 12.
Article in En | MEDLINE | ID: mdl-36474045
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Coronary Artery Disease Type of study: Etiology_studies / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2022 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Coronary Artery Disease Type of study: Etiology_studies / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2022 Document type: Article Affiliation country: United States