The design of a randomized, placebo-controlled, dose-ranging trial to investigate the efficacy and safety of the ADAMTS-5 inhibitor S201086/GLPG1972 in knee osteoarthritis.

Imbert, Olivier; Deckx, Henri; Bernard, Katy; van der Aar, Ellen; Pueyo, Maria; Saeed, Nadeem; Fuerst, Thomas; Wirth, Wolfgang; Conaghan, Philip G; Eckstein, Felix

Imbert, Olivier; Deckx, Henri; Bernard, Katy; van der Aar, Ellen; Pueyo, Maria; Saeed, Nadeem; Fuerst, Thomas; Wirth, Wolfgang; Conaghan, Philip G; Eckstein, Felix.

Affiliation

Imbert O; Institut de Recherches Internationales Servier (IRIS), Suresnes, France.
Deckx H; Galapagos NV, Mechelen, Belgium.
Bernard K; Institut de Recherches Internationales Servier (IRIS), Suresnes, France.
van der Aar E; Galapagos NV, Mechelen, Belgium.
Pueyo M; Institut de Recherches Internationales Servier (IRIS), Suresnes, France.
Saeed N; Bioclinica, London, UK.
Fuerst T; Bioclinica, Newark, CA, USA.
Wirth W; Chondrometrics GmbH, Ainring, Germany.
Conaghan PG; Institute of Anatomy and Cell Biology and Ludwig Boltzmann Institute for Arthritis and Rehabilitation (LBIAR), Paracelsus Medical University, Salzburg, Austria.
Eckstein F; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Biomedical Research Centre, UK.

Osteoarthr Cartil Open ; 3(4): 100209, 2021 Dec.

Article in En | MEDLINE | ID: mdl-36474770

Key words

ADAMTS-5 inhibitor; Cartilage; Clinical trial; Disease modification; Knee osteoarthritis; Quantitative magnetic resonance imaging

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Clinical_trials Aspects: Patient_preference Language: En Journal: Osteoarthr Cartil Open Year: 2021 Document type: Article Affiliation country: France Country of publication: United kingdom

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google