Proteomics reveals the potential mechanism of Tanshinone IIA in promoting the Ex Vivo expansion of human bone marrow mesenchymal stem cells.
Regen Ther
; 21: 560-573, 2022 Dec.
Article
in En
| MEDLINE
| ID: mdl-36475023
Autocrine; BMSCs, bone marrow mesenchymal stem cells; Bone marrow mesenchymal stem cells; CDK, cyclin-dependent kinase; COG, Clusters of Orthologous Groups of proteins; DEPs, differentially expressed proteins; DMSO, dimethyl sulfoxide; EdU, 5' Ethynyl 2' deoxyuridine; Expansion; FC, Fold Change; FDR, false discovery rate; FGF1/2, fibroblast growth factor 1/2; FGFR, FGF receptor; Fibroblast growth factor 2; GO, Gene Ontology; HPLC, high performance liquid chromatography; KEGG, Encyclopedia of Genes and Genomes; LC-MS, liquid chromatography-mass spectrometry; MTT, Three-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PCNA, proliferating cell nuclear antigen; PPI, proteinprotein interactions; Proteomics; TEAB, triethylammonium bicarbonate; TMT, tendam mass tags; Tan IIA, Tanshinone IIA; Tanshinone IIA
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Type of study:
Prognostic_studies
Language:
En
Journal:
Regen Ther
Year:
2022
Document type:
Article
Affiliation country:
China
Country of publication:
Netherlands