Relative Humidity Cycling: Implications on the Stability of Moisture-Sensitive Drugs in Solid Pharmaceutical Products.

Veronica, Natalia; Heng, Paul Wan Sia; Liew, Celine Valeria

Veronica, Natalia; Heng, Paul Wan Sia; Liew, Celine Valeria.

Affiliation

Veronica N; GEA-NUS Pharmaceutical Processing Research Laboratory, Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore117543, Singapore.
Heng PWS; GEA-NUS Pharmaceutical Processing Research Laboratory, Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore117543, Singapore.
Liew CV; School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, 47500 Subang Jaya, Selangor, Malaysia.

Mol Pharm ; 20(2): 1072-1085, 2023 02 06.

Article in En | MEDLINE | ID: mdl-36480246

Subject(s)

Excipients; Lactose; Excipients/chemistry; Humidity; Starch/chemistry; Tablets/chemistry; Aspirin/chemistry; Drug Stability; Mannitol/chemistry

Key words

excipients; moisture history; moisture sorption; relative humidity cycling; stability

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Excipients / Lactose Type of study: Diagnostic_studies Language: En Journal: Mol Pharm Journal subject: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Year: 2023 Document type: Article Affiliation country: Singapore Country of publication: United States

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