Hexane fraction of <i>Globimetula braunii</i> induces mitochondria-mediated apoptosis in <i>Plasmodium berghei</i>-infected mice.

Olanlokun, John Oludele; Ekundayo, Mercy Toluwase; Koorbanally, Neil Anthony; Olorunsogo, Olufunso Olabode

Hexane fraction of Globimetula braunii induces mitochondria-mediated apoptosis in Plasmodium berghei-infected mice.

Olanlokun, John Oludele; Ekundayo, Mercy Toluwase; Koorbanally, Neil Anthony; Olorunsogo, Olufunso Olabode.

Affiliation

Olanlokun JO; Laboratories for Biomembrane Research and Biotechnology, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Nigeria.
Ekundayo MT; Laboratories for Biomembrane Research and Biotechnology, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Nigeria.
Koorbanally NA; School of Chemistry and Physics, University of KwaZulu-Natal, Durban 4000, South Africa.
Olorunsogo OO; Laboratories for Biomembrane Research and Biotechnology, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Nigeria.

Toxicol Rep ; 9: 769-777, 2022.

Article in En | MEDLINE | ID: mdl-36518384

Key words

ANOVA, Analysis of variance; ATP, Adenosine triphosphate; Apoptosis; BSA, Bovine serum albumin; Bax, Bcl2-Associated X protein; Bcl2, B cell lymphoma 2; CaCl2, Calcium chloride; Caspases; CuSO4, Copper (II) tetraoxo sulfate (VI); Cytochrome c; DMSO, Dimethylsulfoxide; DNA, Deoxyribonucleic acid; EDTA, Ethylene diamine tetraacetic acid; EGTA, ethylene glycol-bis(ß-aminoethyl ether)-N,N,N',N'-tetraacetic acid; ELISA, Enzyme-linked immunosorbent assay; FID, Flame ionization detector; GC-MS, Gas chromatography-mass spectrometry; Globimetula braunii; HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; HFGB, Hexane fraction of Globimetula braunii; KOH, Potassium hydroxide; Malaria; Na2CO3, Sodium trioxocarbonate (IV); SDS, Sodium dodecysulfate; Tris-HCl, Tris(hydroxymethyl)aminomethane-hydrochloric acid; mLPO, Mitochondrial lipid peroxidation; mPT, Mitochondrial permeability transition

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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Toxicol Rep Year: 2022 Document type: Article Affiliation country: Nigeria Country of publication: Ireland

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