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Impact of Sotorasib on the Pharmacokinetics and Pharmacodynamics of Metformin, a MATE1/2K Substrate, in Healthy Subjects.
Vuu, Irene; Wahlstrom, Jan; Houk, Brett E.
Affiliation
  • Vuu I; Clinical Pharmacology Modeling and Simulation, Amgen, Inc., 1 Amgen Center Dr., Thousand Oaks, CA, 91320, USA. ivuu@amgen.com.
  • Wahlstrom J; Pharmacokinetics and Drug Metabolism, Amgen, Inc., San Francisco, CA, USA.
  • Houk BE; Clinical Pharmacology Modeling and Simulation, Amgen, Inc., 1 Amgen Center Dr., Thousand Oaks, CA, 91320, USA.
Clin Pharmacokinet ; 62(2): 267-275, 2023 02.
Article in En | MEDLINE | ID: mdl-36529835
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Non-Small-Cell Lung / Lung Neoplasms / Metformin Limits: Humans Language: En Journal: Clin Pharmacokinet Year: 2023 Document type: Article Affiliation country: United States Country of publication: Switzerland
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Non-Small-Cell Lung / Lung Neoplasms / Metformin Limits: Humans Language: En Journal: Clin Pharmacokinet Year: 2023 Document type: Article Affiliation country: United States Country of publication: Switzerland