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Co-targeting triple-negative breast cancer cells and endothelial cells by metronomic chemotherapy inhibits cell regrowth and migration via downregulation of the FAK/VEGFR2/VEGF axis and autophagy/apoptosis activation.
Scagliotti, Arianna; Capizzi, Laura; Cazzaniga, Marina Elena; Ilari, Alice; De Giorgi, Marco; Cordani, Nicoletta; Gallazzi, Matteo; Bruno, Antonino; Pelosi, Giuseppe; Albini, Adriana; Lavitrano, Marialuisa; Grassilli, Emanuela; Cerrito, Maria Grazia.
Affiliation
  • Scagliotti A; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
  • Capizzi L; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
  • Cazzaniga ME; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
  • Ilari A; Phase 1 Research Center, Azienda Socio Sanitaria Territoriale (ASST) di Monza, Monza, Italy.
  • De Giorgi M; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
  • Cordani N; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
  • Gallazzi M; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
  • Bruno A; Laboratory of Immunology and General Pathology, Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.
  • Pelosi G; Laboratory of Immunology and General Pathology, Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.
  • Albini A; Laboratory of Innate Immunity, Unit of Molecular Pathology, Biochemistry and Immunology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) MultiMedica, Milan, Italy.
  • Lavitrano M; Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) MultiMedica, Milan, Italy.
  • Grassilli E; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.
  • Cerrito MG; IRCCS European Institute of Oncology (IEO), Milan, Italy.
Front Oncol ; 12: 998274, 2022.
Article in En | MEDLINE | ID: mdl-36531071
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Front Oncol Year: 2022 Document type: Article Affiliation country: Italy Country of publication: Switzerland
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Front Oncol Year: 2022 Document type: Article Affiliation country: Italy Country of publication: Switzerland