A Versatile Strategy for Screening Custom-Designed Warhead-Armed Cyclic Peptide Inhibitors.

Kang, Deokhee; Kim, Do-Wook; Kim, Joo-Chan; Park, Hee-Sung

Kang, Deokhee; Kim, Do-Wook; Kim, Joo-Chan; Park, Hee-Sung.

Affiliation

Kang D; Department of Chemistry, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu, Daejeon, 34141, Korea.
Kim DW; Department of Chemistry, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu, Daejeon, 34141, Korea.
Kim JC; Department of Chemistry, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu, Daejeon, 34141, Korea.
Park HS; Department of Chemistry, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu, Daejeon, 34141, Korea.

Angew Chem Int Ed Engl ; 62(7): e202214815, 2023 02 06.

Article in En | MEDLINE | ID: mdl-36535892

Subject(s)

Peptides, Cyclic; Peptides; Humans; Peptides, Cyclic/chemistry; Peptides/chemistry; Inteins; Amino Acids/metabolism; Protein Splicing; Histone Deacetylase Inhibitors; Histone Deacetylases/metabolism; Repressor Proteins/metabolism

Key words

Cyclic Peptide Inhibitor; Genetic Code Expansion; Warhead-Bearing Unnatural Amino Acid

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Peptides, Cyclic Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: Angew Chem Int Ed Engl Year: 2023 Document type: Article Country of publication: Germany

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