The UBE2C/CDH1/DEPTOR axis is an oncogene and tumor suppressor cascade in lung cancer cells.

Zhang, Shizhen; You, Xiahong; Zheng, Yawen; Shen, Yanwen; Xiong, Xiufang; Sun, Yi

Zhang, Shizhen; You, Xiahong; Zheng, Yawen; Shen, Yanwen; Xiong, Xiufang; Sun, Yi.

Affiliation

Zhang S; Cancer Institute and.
You X; Department of Breast Surgery and Oncology, Key Laboratory of Cancer Prevention and Intervention, Ministry of Education, the Second Affiliated Hospital, and.
Zheng Y; Cancer Institute and.
Shen Y; Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, China.
Xiong X; Cancer Institute and.
Sun Y; Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, China.

J Clin Invest ; 133(4)2023 02 15.

Article in En | MEDLINE | ID: mdl-36548081

Subject(s)

Lung Neoplasms; Tumor Suppressor Proteins; Ubiquitin-Conjugating Enzymes; Animals; Humans; Mice; Cell Line, Tumor; Cell Proliferation/genetics; Lung Neoplasms/genetics; Lung Neoplasms/metabolism; Oncogenes; Proto-Oncogene Proteins p21(ras)/genetics; Proto-Oncogene Proteins p21(ras)/metabolism; Tumor Suppressor Proteins/metabolism; Ubiquitin-Conjugating Enzymes/genetics; Ubiquitin-Conjugating Enzymes/metabolism; Cdh1 Proteins/metabolism

Key words

Cell Biology; Lung cancer; Oncology; Ubiquitin-proteosome system

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Suppressor Proteins / Ubiquitin-Conjugating Enzymes / Lung Neoplasms Limits: Animals / Humans Language: En Journal: J Clin Invest Year: 2023 Document type: Article Country of publication: United States

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