A Listeria-based vaccine targeting ISG15 exerts anti-tumor efficacy in renal cell carcinoma.

Nguyen, Hong-My; Oladejo, Mariam; Paulishak, Wyatt; Wood, Laurence M

Nguyen, Hong-My; Oladejo, Mariam; Paulishak, Wyatt; Wood, Laurence M.

Affiliation

Nguyen HM; Department of Immunotherapeutics and Biotechnology, Jerry H Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA.
Oladejo M; Department of Immunotherapeutics and Biotechnology, Jerry H Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA.
Paulishak W; Department of Immunotherapeutics and Biotechnology, Jerry H Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA.
Wood LM; Department of Immunotherapeutics and Biotechnology, Jerry H Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA. laurence.wood@ttuhsc.edu.

Cancer Immunol Immunother ; 72(9): 2889-2903, 2023 Sep.

Article in En | MEDLINE | ID: mdl-36562824

Subject(s)

Antigens, Neoplasm; Cancer Vaccines; Carcinoma, Renal Cell; Cytokines; Kidney Neoplasms; Listeria monocytogenes; Ubiquitins; Animals; Humans; Male; Mice; Antigens, Neoplasm/immunology; Cancer Vaccines/immunology; Cancer Vaccines/therapeutic use; Carcinoma, Renal Cell/immunology; Carcinoma, Renal Cell/therapy; Cell Line, Tumor; Cytokines/antagonists & inhibitors; Cytokines/immunology; Immune Checkpoint Inhibitors/therapeutic use; Kidney Neoplasms/immunology; Kidney Neoplasms/therapy; Listeria monocytogenes/immunology; Lymphocytes, Tumor-Infiltrating/immunology; Mice, Inbred BALB C; NIH 3T3 Cells; Sunitinib/therapeutic use; T-Lymphocytes/immunology; Ubiquitins/antagonists & inhibitors; Ubiquitins/immunology; Tumor Microenvironment/immunology

Key words

Anti-PD-1; Interferon-stimulated gene 15; Listeria-based vaccines; Renal cell carcinoma; Sunitinib

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Renal Cell / Ubiquitins / Cytokines / Cancer Vaccines / Kidney Neoplasms / Listeria monocytogenes / Antigens, Neoplasm Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans / Male Language: En Journal: Cancer Immunol Immunother Journal subject: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Year: 2023 Document type: Article Affiliation country: United States Country of publication: Germany

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