Streptonigrin and lavendamycin partial structures. Probes for the minimum, potent pharmacophore of streptonigrin, lavendamycin, and synthetic quinoline-5,8-diones.

Boger, D L; Yasuda, M; Mitscher, L A; Drake, S D; Kitos, P A; Thompson, S C

Boger, D L; Yasuda, M; Mitscher, L A; Drake, S D; Kitos, P A; Thompson, S C.

Affiliation

Boger DL; Department of Chemistry, Purdue University, West Lafayette, Indiana 47907.

J Med Chem ; 30(10): 1918-28, 1987 Oct.

Article in En | MEDLINE | ID: mdl-3656364

Subject(s)

Antibiotics, Antineoplastic/analysis; Quinolines; Streptonigrin/analogs & derivatives; Streptonigrin/analysis; Animals; Antibiotics, Antineoplastic/therapeutic use; Chemical Phenomena; Chemistry, Physical; Leukemia L1210/drug therapy; Melanoma/drug therapy; Mice; Microbial Sensitivity Tests; Streptonigrin/therapeutic use; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Quinolines / Streptonigrin / Antibiotics, Antineoplastic Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 1987 Document type: Article Country of publication: United States

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