Antiviral Activity of Oridonin Against Herpes Simplex Virus Type 1.

Jiang, Kai; Feng, Jing; Qi, Xia; Ran, Lili; Xie, Lixin

Jiang, Kai; Feng, Jing; Qi, Xia; Ran, Lili; Xie, Lixin.

Affiliation

Jiang K; Department of Ophthalmology, the Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, People's Republic of China.
Feng J; Eye Institute of Shandong First Medical University, Eye Hospital of Shandong First Medical University, Qingdao, People's Republic of China.
Qi X; Eye Institute of Shandong First Medical University, Eye Hospital of Shandong First Medical University, Qingdao, People's Republic of China.
Ran L; Eye Institute of Shandong First Medical University, Eye Hospital of Shandong First Medical University, Qingdao, People's Republic of China.
Xie L; Eye Institute of Shandong First Medical University, Eye Hospital of Shandong First Medical University, Qingdao, People's Republic of China.

Drug Des Devel Ther ; 16: 4311-4323, 2022.

Article in En | MEDLINE | ID: mdl-36573068

Subject(s)

Herpes Simplex; Herpesvirus 1, Human; Keratitis, Herpetic; Chlorocebus aethiops; Animals; Mice; Antiviral Agents/pharmacology; Antiviral Agents/therapeutic use; Vero Cells; Dimethyl Sulfoxide/pharmacology; Dimethyl Sulfoxide/therapeutic use; NLR Family, Pyrin Domain-Containing 3 Protein; Mice, Inbred C57BL; Herpes Simplex/drug therapy; Keratitis, Herpetic/drug therapy

Key words

HSV-1; herb; herpes simplex keratitis; inflammasome; nlrp3; oridonin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Keratitis, Herpetic / Herpesvirus 1, Human / Herpes Simplex Type of study: Prognostic_studies Limits: Animals Language: En Journal: Drug Des Devel Ther Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2022 Document type: Article Country of publication: New Zealand

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