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Mutation-agnostic RNA interference with engineered replacement rescues Tmc1-related hearing loss.
Iwasa, Yoichiro; Klimara, Miles J; Yoshimura, Hidekane; Walls, William D; Omichi, Ryotaro; West, Cody A; Shibata, Seiji B; Ranum, Paul T; Smith, Richard Jh.
Affiliation
  • Iwasa Y; Department of Otorhinolaryngology, Shinshu University School of Medicine, Matsumoto, Japan.
  • Klimara MJ; Molecular Otolaryngology and Renal Research Laboratories, Department of Otolaryngology - Head and Neck Surgery, University of Iowa, Iowa City, IA, USA.
  • Yoshimura H; Department of Otolaryngology - Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
  • Walls WD; Molecular Otolaryngology and Renal Research Laboratories, Department of Otolaryngology - Head and Neck Surgery, University of Iowa, Iowa City, IA, USA.
  • Omichi R; Department of Otolaryngology - Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
  • West CA; Molecular Otolaryngology and Renal Research Laboratories, Department of Otolaryngology - Head and Neck Surgery, University of Iowa, Iowa City, IA, USA.
  • Shibata SB; Department of Otolaryngology Head and Neck Surgery, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Ranum PT; Raymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia Research Institute, Philadelphia, PA, USA.
  • Smith RJ; Molecular Otolaryngology and Renal Research Laboratories, Department of Otolaryngology - Head and Neck Surgery, University of Iowa, Iowa City, IA, USA richard-smith@uiowa.edu.
Life Sci Alliance ; 6(3)2023 03.
Article in En | MEDLINE | ID: mdl-36574989
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mechanotransduction, Cellular / Hearing Loss Limits: Animals Language: En Journal: Life Sci Alliance Year: 2023 Document type: Article Affiliation country: Japan Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mechanotransduction, Cellular / Hearing Loss Limits: Animals Language: En Journal: Life Sci Alliance Year: 2023 Document type: Article Affiliation country: Japan Country of publication: United States