Improved joint and patient-reported health assessments with pegloticase plus methotrexate co-therapy in patients with uncontrolled gout: 12-month exploratory outcomes of the MIRROR open-label trial.

Botson, John K; Obermeyer, Katie; LaMoreaux, Brian; Zhao, Lin; Weinblatt, Michael E; Peterson, Jeff

Botson, John K; Obermeyer, Katie; LaMoreaux, Brian; Zhao, Lin; Weinblatt, Michael E; Peterson, Jeff.

Affiliation

Botson JK; Orthopedic Physicians Alaska, 3801 Lake Otis Parkway, Anchorage, AK, 99508, USA. jbotson@opaak.com.
Obermeyer K; Horizon Therapeutics plc, Deerfield, IL, USA.
LaMoreaux B; Horizon Therapeutics plc, Deerfield, IL, USA.
Zhao L; Horizon Therapeutics plc, Deerfield, IL, USA.
Weinblatt ME; Division of Rheumatology, Immunology and Immunity, Brigham and Women's Hospital, Boston, MA, USA.
Peterson J; Western Washington Arthritis Clinic, Bothell, WA, USA.

Arthritis Res Ther ; 24(1): 281, 2022 12 27.

Article in En | MEDLINE | ID: mdl-36575505

Subject(s)

Gout; Uric Acid; Adult; Humans; Methotrexate/therapeutic use; Gout Suppressants/therapeutic use; Quality of Life; Gout/drug therapy; Gout/chemically induced; Polyethylene Glycols/adverse effects; Urate Oxidase/therapeutic use; Treatment Outcome

Key words

Immunomodulation; Methotrexate; Pegloticase; Refractory gout; Uncontrolled gout

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uric Acid / Gout Type of study: Prognostic_studies Aspects: Patient_preference Limits: Adult / Humans Language: En Journal: Arthritis Res Ther Journal subject: REUMATOLOGIA Year: 2022 Document type: Article Affiliation country: United States Country of publication: United kingdom

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google