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Development of a Potent Cyclic Peptide Inhibitor of the nNOS/PSD-95 Interaction.
Balboa, Javier R; Essig, Dominik J; Ma, Sana; Karer, Nichlas; Clemmensen, Louise S; Pedersen, Søren W; Joerger, Andreas C; Knapp, Stefan; Østergaard, Søren; Strømgaard, Kristian.
Affiliation
  • Balboa JR; Novo Nordisk A/S, Research Chemistry 3, Novo Nordisk Park, 2760 Måløv, Denmark.
  • Essig DJ; Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
  • Ma S; Novo Nordisk A/S, Research Chemistry 3, Novo Nordisk Park, 2760 Måløv, Denmark.
  • Karer N; Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
  • Clemmensen LS; Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
  • Pedersen SW; Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
  • Joerger AC; Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
  • Knapp S; Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
  • Østergaard S; Institute of Pharmaceutical Chemistry, Goethe University, Max-von-Laue Str. 9, 60438 Frankfurt am Main, Germany.
  • Strømgaard K; Structural Genomics Consortium (SGC), Buchmann Institute for Molecular Life Sciences (BMLS), Max-von-Laue-Str. 15, 60438 Frankfurt am Main, Germany.
J Med Chem ; 66(1): 976-990, 2023 01 12.
Article in En | MEDLINE | ID: mdl-36580549
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ischemic Stroke Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2023 Document type: Article Affiliation country: Denmark Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ischemic Stroke Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2023 Document type: Article Affiliation country: Denmark Country of publication: United States