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Sequence and structure-guided discovery of a novel NADH-dependent 7ß-hydroxysteroid dehydrogenase for efficient biosynthesis of ursodeoxycholic acid.
Huang, Bin; Yang, Kai; Amanze, Charles; Yan, Zhen; Zhou, Hongbo; Liu, Xueduan; Qiu, Guanzhou; Zeng, Weimin.
Affiliation
  • Huang B; School of Minerals Processing and Bioengineering, Central South University, Hunan 410083, China.
  • Yang K; School of Minerals Processing and Bioengineering, Central South University, Hunan 410083, China.
  • Amanze C; School of Minerals Processing and Bioengineering, Central South University, Hunan 410083, China.
  • Yan Z; School of Minerals Processing and Bioengineering, Central South University, Hunan 410083, China.
  • Zhou H; School of Minerals Processing and Bioengineering, Central South University, Hunan 410083, China.
  • Liu X; School of Minerals Processing and Bioengineering, Central South University, Hunan 410083, China.
  • Qiu G; School of Minerals Processing and Bioengineering, Central South University, Hunan 410083, China.
  • Zeng W; School of Minerals Processing and Bioengineering, Central South University, Hunan 410083, China. Electronic address: zengweimin1024@126.com.
Bioorg Chem ; 131: 106340, 2023 02.
Article in En | MEDLINE | ID: mdl-36586301
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ursodeoxycholic Acid / Hydroxysteroid Dehydrogenases / NAD Language: En Journal: Bioorg Chem Year: 2023 Document type: Article Affiliation country: China Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ursodeoxycholic Acid / Hydroxysteroid Dehydrogenases / NAD Language: En Journal: Bioorg Chem Year: 2023 Document type: Article Affiliation country: China Country of publication: United States