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Discovery of a first-in-class orally available HBV cccDNA inhibitor.
Wang, Li; Zhu, Qihui; Zhang, Jitao David; Zhang, Yaling; Ni, Xiaoju; Xiang, Kunlun; Jiang, Jiaxi; Li, Baocun; Yu, Youjun; Hu, Hui; Zhang, Meifang; Wu, Waikwong; Zeng, Jing; Yan, Zhipeng; Dai, Jieyu; Sun, Kai; Zhang, Xin; Chen, Dongdong; Feng, Song; Sach-Peltason, Lisa; Young, John A T; Gao, Lu.
Affiliation
  • Wang L; Infectious Disease Discovery.
  • Zhu Q; Infectious Disease Discovery.
  • Zhang JD; Pharmaceutical Sciences.
  • Zhang Y; Infectious Disease Discovery.
  • Ni X; Infectious Disease Discovery.
  • Xiang K; Infectious Disease Discovery.
  • Jiang J; Infectious Disease Discovery.
  • Li B; Infectious Disease Discovery.
  • Yu Y; Infectious Disease Discovery.
  • Hu H; Infectious Disease Discovery.
  • Zhang M; Lead Discovery.
  • Wu W; Lead Discovery.
  • Zeng J; Infectious Disease Discovery.
  • Yan Z; Infectious Disease Discovery.
  • Dai J; Pharmaceutical Sciences.
  • Sun K; Pharmaceutical Sciences.
  • Zhang X; Preclinical Chemistry Manufacturing and Controls.
  • Chen D; Medicinal Chemistry.
  • Feng S; Medicinal Chemistry.
  • Sach-Peltason L; Data & Analytics, Roche Pharmaceutical Research and Early Development, Roche Innovation Center Shanghai, Roche Innovation Center Basel.
  • Young JAT; Infectious Disease Discovery. Electronic address: john.young.jy3@Roche.com.
  • Gao L; Infectious Disease Discovery. Electronic address: goodlucksept2016@yahoo.com.
J Hepatol ; 78(4): 742-753, 2023 04.
Article in En | MEDLINE | ID: mdl-36587899
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepatitis B, Chronic Limits: Animals / Humans Language: En Journal: J Hepatol Journal subject: GASTROENTEROLOGIA Year: 2023 Document type: Article Country of publication: Netherlands
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepatitis B, Chronic Limits: Animals / Humans Language: En Journal: J Hepatol Journal subject: GASTROENTEROLOGIA Year: 2023 Document type: Article Country of publication: Netherlands