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Adenosine-Dependent Activation Mechanism of Prodrugs Targeting an Aminoacyl-tRNA Synthetase.
Hoffmann, Guillaume; Le Gorrec, Madalen; Mestdach, Emeline; Cusack, Stephen; Salmon, Loïc; Jensen, Malene Ringkjøbing; Palencia, Andrés.
Affiliation
  • Hoffmann G; Institute for Advanced Biosciences (IAB), Structural Biology of Novel Targets in Human Diseases, INSERM U1209, CNRS UMR5309, Université Grenoble Alpes, 38000 Grenoble, France.
  • Le Gorrec M; Institute for Advanced Biosciences (IAB), Structural Biology of Novel Targets in Human Diseases, INSERM U1209, CNRS UMR5309, Université Grenoble Alpes, 38000 Grenoble, France.
  • Mestdach E; Centre de Résonance Magnétique Nucléaire à Très Hauts Champs, (CRMN), UMR 5082, CNRS, ENS Lyon, UCBL, Université de Lyon, 69100 Villeurbanne, France.
  • Cusack S; European Molecular Biology Laboratory, 38042 Grenoble, France.
  • Salmon L; Centre de Résonance Magnétique Nucléaire à Très Hauts Champs, (CRMN), UMR 5082, CNRS, ENS Lyon, UCBL, Université de Lyon, 69100 Villeurbanne, France.
  • Jensen MR; Université Grenoble Alpes, CEA, CNRS, IBS, 38044 Grenoble, France.
  • Palencia A; Institute for Advanced Biosciences (IAB), Structural Biology of Novel Targets in Human Diseases, INSERM U1209, CNRS UMR5309, Université Grenoble Alpes, 38000 Grenoble, France.
J Am Chem Soc ; 145(2): 800-810, 2023 01 18.
Article in En | MEDLINE | ID: mdl-36599057
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prodrugs / Amino Acyl-tRNA Synthetases / Leucine-tRNA Ligase Limits: Humans Language: En Journal: J Am Chem Soc Year: 2023 Document type: Article Affiliation country: France
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prodrugs / Amino Acyl-tRNA Synthetases / Leucine-tRNA Ligase Limits: Humans Language: En Journal: J Am Chem Soc Year: 2023 Document type: Article Affiliation country: France