Your browser doesn't support javascript.
loading
Implementation of a home-based colorectal cancer screening intervention in Malaysia (CRC-SIM).
Schliemann, Désirée; Ramanathan, Kogila; Ibrahim Tamin, Nor Saleha Binti; O'Neill, Ciaran; Cardwell, Christopher R; Ismail, Roshidi; Kassim, Zaid; Kee, Frank; Su, Tin Tin; Donnelly, Michael.
Affiliation
  • Schliemann D; Centre for Public Health and UKCRC Centre of Excellence for Public Health, Queen's University Belfast, Belfast, UK. d.schliemann@qub.ac.uk.
  • Ramanathan K; Global Public Health, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Selangor, Malaysia.
  • Ibrahim Tamin NSB; South East Asia Community Observatory (SEACO), Jeffrey Cheah School of Medicine and Health Sciences, Monash University, Petaling Jaya, Malaysia.
  • O'Neill C; Ministry of Health Malaysia, Putrajaya, Malaysia.
  • Cardwell CR; Centre for Public Health and UKCRC Centre of Excellence for Public Health, Queen's University Belfast, Belfast, UK.
  • Ismail R; Centre for Public Health and UKCRC Centre of Excellence for Public Health, Queen's University Belfast, Belfast, UK.
  • Kassim Z; Global Public Health, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Selangor, Malaysia.
  • Kee F; South East Asia Community Observatory (SEACO), Jeffrey Cheah School of Medicine and Health Sciences, Monash University, Petaling Jaya, Malaysia.
  • Su TT; Segamat District Health Office, Johor, Malaysia.
  • Donnelly M; Centre for Public Health and UKCRC Centre of Excellence for Public Health, Queen's University Belfast, Belfast, UK.
BMC Cancer ; 23(1): 22, 2023 Jan 06.
Article in En | MEDLINE | ID: mdl-36609260
INTRODUCTION: The Colorectal Cancer Screening Intervention for Malaysia (CRC-SIM) was a CRC study of home-based testing designed to improve low screening uptake using the immunochemical fecal occult blood test (iFOBT) in Malaysia. METHODS: This quasi-experimental study was informed by the Implementation Research Logic Model and evaluated with the RE-AIM framework. Trained data collectors recruited by phone, randomly selected, asymptomatic adults aged 50-75 years from Segamat District, who previously completed a health census form for the South East Asia Community Observatory (SEACO). Participants were posted an iFOBT kit and asked to return a photo of the completed test for screening by health care professionals. A regression analysis of evaluation data was conducted to identify which variables were associated with the outcome indicators of 'study participation' and 'iFOBT completion' and the CRC-SIM was evaluated in terms of its appropriateness, feasibility and acceptability. RESULTS: Seven hundred forty-seven eligible adults (52%) agreed to participate in this study and received an iFOBT kit. Participation was significantly lower amongst Chinese Malaysians (adjusted OR 0.45, 95% CI 0.35 - 0.59, p<0.001) compared to Malays and amongst participants from the rural sub-district (Gemereh) (adjusted OR 0.71, 95% CI 0.54 - 0.92, p=0.011) compared to the urban sub-district (Sungai Segamat). Less than half of participants (42%, n=311/747) completed the iFOBT. Test-kit completion was significantly higher amongst Chinese Malaysians (adjusted OR 3.15, 95% CI 2.11 - 4.69, p<0.001) and lower amongst participants with a monthly household income ≥RM 4,850 (adjusted OR 0.58, 95% CI 0.39 - 0.87, p=0.009) compared to participants with a lower household income. The main reported reason for non-participation was 'not interested' (58.6%) and main implementation challenges related to invalid photographs from participants and engaging iFOBT positive participants in further clinic consultations and procedures. CONCLUSION: Home-testing for CRC (test completion) appeared to be acceptable to only around one-fifth of the target population in Malaysia. However, mindful of the challenging circumstances surrounding the pandemic, the CRC-SIM merits consideration by public health planners as a method of increasing screening in Malaysia, and other low- and middle-income countries.
Subject(s)
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Early Detection of Cancer Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Adult / Humans Country/Region as subject: Asia Language: En Journal: BMC Cancer Journal subject: NEOPLASIAS Year: 2023 Document type: Article Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Early Detection of Cancer Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Adult / Humans Country/Region as subject: Asia Language: En Journal: BMC Cancer Journal subject: NEOPLASIAS Year: 2023 Document type: Article Country of publication: United kingdom