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Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA.1-BA.5.
Wang, Yanqun; Yan, An; Song, Deyong; Dong, Chuangchuang; Rao, Muding; Gao, Yuanzhu; Qi, Ruxi; Ma, Xiaomin; Wang, Qiaoping; Xu, Hongguang; Liu, Hong; Han, Jing; Duan, Maoqin; Liu, Shuo; Yu, Xiaoping; Zong, Mengqi; Feng, Jianxia; Jiao, Jie; Zhang, Huimin; Li, Min; Yu, Beibei; Wang, Yanxia; Meng, Fanhao; Ni, Xiaodan; Li, Ying; Shen, Zhenduo; Sun, Baiping; Shao, Xin; Zhao, Haifeng; Zhao, Yanyan; Li, Rui; Zhang, Yanan; Du, Guangying; Lu, Jun; You, Chunna; Jiang, Hua; Zhang, Lu; Wang, Lan; Dou, Changlin; Liu, Zheng; Zhao, Jincun.
Affiliation
  • Wang Y; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
  • Yan A; GMU-GIBH Joint School of Life Sciences, Guangzhou Medical University, Guangzhou, Guangdong, China.
  • Song D; Cryo-electron Microscopy Center, Southern University of Science and Technology, Shenzhen, Guangdong, China.
  • Dong C; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Rao M; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Gao Y; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Qi R; Cryo-electron Microscopy Center, Southern University of Science and Technology, Shenzhen, Guangdong, China.
  • Ma X; Cryo-electron Microscopy Center, Southern University of Science and Technology, Shenzhen, Guangdong, China.
  • Wang Q; Cryo-electron Microscopy Center, Southern University of Science and Technology, Shenzhen, Guangdong, China.
  • Xu H; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Liu H; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Han J; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Duan M; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Liu S; Division of Monoclonal Antibodies, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, China.
  • Yu X; Division of Monoclonal Antibodies, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, China.
  • Zong M; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Feng J; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Jiao J; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Zhang H; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Li M; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Yu B; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Wang Y; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Meng F; Shuimu BioSciences Ltd, Beijing, China.
  • Ni X; Shuimu BioSciences Ltd, Beijing, China.
  • Li Y; Shuimu BioSciences Ltd, Beijing, China.
  • Shen Z; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Sun B; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Shao X; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Zhao H; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Zhao Y; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Li R; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Zhang Y; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Du G; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Lu J; State Key Laboratory of Long-acting and Targeting Drug Delivery System, Shandong Luye Pharmaceutical Co. Ltd, Yantai, Shandong, China.
  • You C; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Jiang H; State Key Laboratory of Long-acting and Targeting Drug Delivery System, Shandong Luye Pharmaceutical Co. Ltd, Yantai, Shandong, China.
  • Zhang L; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China.
  • Wang L; Health and Quarantine Laboratory, Guangzhou Customs District Technology Centre, Guangzhou, Guangdong, China.
  • Dou C; Division of Monoclonal Antibodies, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, China. wanglan@nifdc.org.cn.
  • Liu Z; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, Shandong, China. douchanglin@boan-bio.com.
  • Zhao J; Cryo-electron Microscopy Center, Southern University of Science and Technology, Shenzhen, Guangdong, China. liuz3@sustech.edu.cn.
Cell Discov ; 9(1): 3, 2023 Jan 07.
Article in En | MEDLINE | ID: mdl-36609558
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Cell Discov Year: 2023 Document type: Article Affiliation country: China Country of publication: United kingdom
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Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Cell Discov Year: 2023 Document type: Article Affiliation country: China Country of publication: United kingdom