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RGD density along with substrate stiffness regulate hPSC hepatocyte functionality through YAP signalling.
Blackford, Samuel J I; Yu, Tracy T L; Norman, Michael D A; Syanda, Adam M; Manolakakis, Michail; Lachowski, Dariusz; Yan, Ziqian; Guo, Yunzhe; Garitta, Elena; Riccio, Federica; Jowett, Geraldine M; Ng, Soon Seng; Vernia, Santiago; Del Río Hernández, Armando E; Gentleman, Eileen; Rashid, S Tamir.
Affiliation
  • Blackford SJI; Department of Metabolism, Digestion and Reproduction, Imperial College London, UK; Centre for Craniofacial & Regenerative Biology, King's College London, UK; Centre for Gene Therapy & Regenerative Medicine, King's College London, UK; NIHR Imperial BRC iPSC and Organoid Core Facility, Imperia
  • Yu TTL; Centre for Craniofacial & Regenerative Biology, King's College London, UK.
  • Norman MDA; Centre for Craniofacial & Regenerative Biology, King's College London, UK.
  • Syanda AM; Department of Metabolism, Digestion and Reproduction, Imperial College London, UK; NIHR Imperial BRC iPSC and Organoid Core Facility, Imperial College London, UK.
  • Manolakakis M; MRC London Institute of Medical Sciences, UK; Institute of Clinical Sciences, Imperial College London, UK.
  • Lachowski D; Cellular and Molecular Biomechanics Laboratory, Department of Bioengineering, Imperial College London, UK.
  • Yan Z; Centre for Craniofacial & Regenerative Biology, King's College London, UK.
  • Guo Y; Centre for Craniofacial & Regenerative Biology, King's College London, UK.
  • Garitta E; Department of Metabolism, Digestion and Reproduction, Imperial College London, UK; NIHR Imperial BRC iPSC and Organoid Core Facility, Imperial College London, UK.
  • Riccio F; Centre for Gene Therapy & Regenerative Medicine, King's College London, UK.
  • Jowett GM; Centre for Craniofacial & Regenerative Biology, King's College London, UK; Centre for Gene Therapy & Regenerative Medicine, King's College London, UK.
  • Ng SS; Department of Metabolism, Digestion and Reproduction, Imperial College London, UK; NIHR Imperial BRC iPSC and Organoid Core Facility, Imperial College London, UK.
  • Vernia S; MRC London Institute of Medical Sciences, UK; Institute of Clinical Sciences, Imperial College London, UK.
  • Del Río Hernández AE; Cellular and Molecular Biomechanics Laboratory, Department of Bioengineering, Imperial College London, UK.
  • Gentleman E; Centre for Craniofacial & Regenerative Biology, King's College London, UK. Electronic address: eileen.gentleman@kcl.ac.uk.
  • Rashid ST; Department of Metabolism, Digestion and Reproduction, Imperial College London, UK; NIHR Imperial BRC iPSC and Organoid Core Facility, Imperial College London, UK. Electronic address: t.rashid@imperial.ac.uk.
Biomaterials ; 293: 121982, 2023 02.
Article in En | MEDLINE | ID: mdl-36640555
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Hepatocytes Limits: Humans Language: En Journal: Biomaterials Year: 2023 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Hepatocytes Limits: Humans Language: En Journal: Biomaterials Year: 2023 Document type: Article