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Design, synthesis and biological evaluation of novel 9-N-substituted-13-alkylberberine derivatives from Chinese medicine as anti-hepatocellular carcinoma agents.
Chen, Jichao; Duan, Yiping; Yang, Kan; Wang, Jiahe; Yan, Junjie; Gu, Chenglei; Wang, Shanglong; Zhu, Zheying; Liu, E-Hu; Xu, Jinyi.
Affiliation
  • Chen J; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China. Electronic address: chenjichao@njucm.edu.cn.
  • Duan Y; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, China.
  • Yang K; Key Laboratory of Pharmaceutical Quality Control of Hebei Province, College of Pharmaceutical Sciences, Hebei University, Baoding 071002, China.
  • Wang J; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
  • Yan J; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
  • Gu C; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
  • Wang S; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
  • Zhu Z; Division of Molecular Therapeutics & Formulation, School of Pharmacy, the University of Nottingham, University Park Campus, Nottingham NG7 2RD, UK.
  • Liu EH; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China. Electronic address: liuehu2011@163.com.
  • Xu J; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, China. Electronic address: jinyixu@china.com.
Bioorg Med Chem ; 79: 117156, 2023 02 01.
Article in En | MEDLINE | ID: mdl-36640595
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Hepatocellular / Liver Neoplasms / Antineoplastic Agents Type of study: Diagnostic_studies Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2023 Document type: Article Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Hepatocellular / Liver Neoplasms / Antineoplastic Agents Type of study: Diagnostic_studies Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2023 Document type: Article Country of publication: United kingdom