Your browser doesn't support javascript.
loading
Prevalence and Associated Factors of Facet Joint Ankylosis in Patients With Axial Spondyloarthritis.
Lee, Bong-Woo; Jung, Joon-Yong; Kim, Moon-Young; Hong, Yeon Sik; Park, Sung-Hwan; Kang, Kwi Young.
Affiliation
  • Lee BW; B.W. Lee, MD, S.H. Park, MD, PhD, Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul.
  • Jung JY; J.Y. Jung, MD, PhD, Department of Radiology, College of Medicine, The Catholic University of Korea, Seoul.
  • Kim MY; M.Y. Kim, MD, Y.S. Hong, MD, PhD, K.Y. Kang, MD, PhD, Division of Rheumatology, Department of Internal Medicine, Incheon Saint Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, and Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Cathol
  • Hong YS; M.Y. Kim, MD, Y.S. Hong, MD, PhD, K.Y. Kang, MD, PhD, Division of Rheumatology, Department of Internal Medicine, Incheon Saint Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, and Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Cathol
  • Park SH; B.W. Lee, MD, S.H. Park, MD, PhD, Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul.
  • Kang KY; M.Y. Kim, MD, Y.S. Hong, MD, PhD, K.Y. Kang, MD, PhD, Division of Rheumatology, Department of Internal Medicine, Incheon Saint Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, and Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Cathol
J Rheumatol ; 50(6): 763-768, 2023 06.
Article in En | MEDLINE | ID: mdl-36642426
ABSTRACT

OBJECTIVE:

To investigate the prevalence of facet joint ankylosis in the whole spine in axial spondyloarthritis (axSpA) using low-dose computed tomography (LDCT), and to identify factors associated with facet joint ankylosis.

METHODS:

Whole spine LDCT images from 161 patients with axSpA were examined, and the presence of facet joint ankylosis was assessed (right and left, C2-S1) by 2 readers. Facet joint ankylosis was scored from 0 to 46. Structural damage of vertebral body was assessed using CT Syndesmophyte Score (CTSS). Factors associated with ankylosed facet joint scores for the whole spine were identified using a generalized linear model with a negative binomial distribution.

RESULTS:

Seventy-nine patients (49%) and 70 patients (43%; reader 1 and reader 2, respectively) had ≥ 1 ankylosed facet joint. Facet joint ankylosis was most common in the thoracic spine. The mean score of facet joint ankylosis for the whole spine was 6.6 (SD 11.2) in reader 1 and 4.2 (SD 8.4) in reader 2. Whole spine facet joint ankylosis score positively correlated with Ankylosing Spondylitis Disease Activity Score (ASDAS) and CTSS. In multivariable analysis, the ankylosed facet joint score was associated with ASDAS, sacroiliitis, CTSS, and a history of uveitis in both readers. Uveitis history, ASDAS, and CTSS were associated with whole spine facet joint ankylosis score in subgroup analysis of only radiographic axSpA.

CONCLUSION:

The prevalence of ankylosed facet joints is high in axSpA, especially in the thoracic segment. The whole spine ankylosed facet joint score is significantly associated with a history of uveitis, ASDAS, sacroiliitis, and syndesmophyte score.
Subject(s)
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spondylitis, Ankylosing / Zygapophyseal Joint / Spondylarthritis / Sacroiliitis Type of study: Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: J Rheumatol Year: 2023 Document type: Article
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spondylitis, Ankylosing / Zygapophyseal Joint / Spondylarthritis / Sacroiliitis Type of study: Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: J Rheumatol Year: 2023 Document type: Article