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Design and synthesis of benzochromene derivatives as AcrB inhibitors for the reversal of bacterial multidrug resistance.
Guo, Ting; Chen, Yang; Chen, Weijin; Semple, Susan J; Gu, Xiaotong; Polyak, Steven W; Sun, Guanglin; Venter, Henrietta; Ma, Shutao.
Affiliation
  • Guo T; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, 250012, China.
  • Chen Y; Health and Biomedical Innovation, Clinical and Health Sciences, University of South Australia, Adelaide, SA, 5000, Australia.
  • Chen W; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, 250012, China.
  • Semple SJ; Quality Use of Medicines and Pharmacy Research Centre, Clinical and Health Sciences, University of South Australia, Adelaide, SA, 5000, Australia.
  • Gu X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, 250012, China.
  • Polyak SW; Health and Biomedical Innovation, Clinical and Health Sciences, University of South Australia, Adelaide, SA, 5000, Australia.
  • Sun G; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, 250012, China.
  • Venter H; Health and Biomedical Innovation, Clinical and Health Sciences, University of South Australia, Adelaide, SA, 5000, Australia. Electronic address: rietie.venter@unisa.edu.au.
  • Ma S; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, 250012, China. Electronic address: mashutao@sdu.edu.cn.
Eur J Med Chem ; 249: 115148, 2023 Mar 05.
Article in En | MEDLINE | ID: mdl-36709649
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Escherichia coli Proteins Language: En Journal: Eur J Med Chem Year: 2023 Document type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Escherichia coli Proteins Language: En Journal: Eur J Med Chem Year: 2023 Document type: Article Affiliation country: China