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Transfusions with laboratory-grown red blood cells: a new development in science.
Kutikuppala, Lakshmi Venkata Simhachalam; Ponnaganti, Sai Venkata Kalyani; Kale, Sampreeti Sri Sai; Kode, Rohith; Kuchana, Sai Kiran.
Affiliation
  • Kutikuppala LVS; Department of General Surgery, Dr NTR University of Health Sciences, Vijayawada, Andhra Pradesh, India. Electronic address: simhachalam.kutikuppala@gmail.com.
  • Ponnaganti SVK; Rangaraya Medical College, Kakinada, Andhra Pradesh, India.
  • Kale SSS; Kakatiya Medical College, Warangal, Telangana, India.
  • Kode R; Kakatiya Medical College, Warangal, Telangana, India.
  • Kuchana SK; Kakatiya Medical College, Warangal, Telangana, India.
Exp Hematol ; 119-120: 1-2, 2023.
Article in En | MEDLINE | ID: mdl-36709794
It is inevitable to anticipate the development of laboratory abilities and their involvement in clinical research in a fast-paced world. The RESTORE study is one such incident that has drawn the interest of various specialists. Red blood cells (RBCs) that have been generated in a laboratory have been transfused into a volunteer in this trial. To our knowledge, this procedure was the first to deliver laboratory-grown cells to another individual through a blood transfusion, which is an advancement in laboratory innovations. The purpose of the research was to determine how long a mini-transfusion of up to two teaspoons or 10 mL of laboratory-grown RBCs will persist in the body in comparison with an equivalent quantity of regular cells from the same donor. Assuming the process can be scaled up to a standard transfusion, this approach is advantageous because it can address the shortage of donors for those with rare blood types. Laboratory-grown blood cells are anticipated to last longer and perform better, which is another benefit to be noticed. This study represents a tremendous advancement in scientific innovation and teamwork while providing high-quality care to those who need it the most, although additional trials are required before clinical usage.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Transfusion / Erythrocyte Transfusion Limits: Humans Language: En Journal: Exp Hematol Year: 2023 Document type: Article Country of publication: Netherlands

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Transfusion / Erythrocyte Transfusion Limits: Humans Language: En Journal: Exp Hematol Year: 2023 Document type: Article Country of publication: Netherlands