Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors.

Umiker, Ben; Hashambhoy-Ramsay, Yasmin; Smith, Jeff; Rahman, Tanzila; Mueller, Amy; Davidson, Rachel; Meyer, Christina; Patankar, Gayatri; Alam, Mohammad Murshid; Jaffe, Sarah; Krukenberg, Kristin; Goodman, Allison; Spaulding, Vikki; Priess, Michelle; Dhaneshwar, Abha; Wong, Masie; Diiorio, Alexa; O'Malley, Kristin; McGrath, Lara; Willer, Margaret; Pepper, Lauren; Gostissa, Monica; Kis-Toth, Katalin; Wiederschain, Dmitri; Cohen, Heather; Shaffer, Donald R

Umiker, Ben; Hashambhoy-Ramsay, Yasmin; Smith, Jeff; Rahman, Tanzila; Mueller, Amy; Davidson, Rachel; Meyer, Christina; Patankar, Gayatri; Alam, Mohammad Murshid; Jaffe, Sarah; Krukenberg, Kristin; Goodman, Allison; Spaulding, Vikki; Priess, Michelle; Dhaneshwar, Abha; Wong, Masie; Diiorio, Alexa; O'Malley, Kristin; McGrath, Lara; Willer, Margaret; Pepper, Lauren; Gostissa, Monica; Kis-Toth, Katalin; Wiederschain, Dmitri; Cohen, Heather; Shaffer, Donald R.

Mol Cancer Ther ; 22(4): 471-484, 2023 04 03.

Article in En | MEDLINE | ID: mdl-36780212

Subject(s)

Neoplasms; Humans; Neoplasms/genetics; Neoplasms/metabolism; Macrophages/metabolism; Lymphocyte Activation; Coculture Techniques; T-Lymphocytes; Tumor Microenvironment; Membrane Glycoproteins/genetics; Receptors, Immunologic

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplasms Limits: Humans Language: En Journal: Mol Cancer Ther Journal subject: ANTINEOPLASICOS Year: 2023 Document type: Article Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google