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A fluid biomarker reveals loss of TDP-43 splicing repression in pre-symptomatic ALS.
Irwin, Katherine E; Jasin, Pei; Braunstein, Kerstin E; Sinha, Irika; Bowden, Kyra D; Moghekar, Abhay; Oh, Esther S; Raitcheva, Denitza; Bartlett, Dan; Berry, James D; Traynor, Bryan; Ling, Jonathan P; Wong, Philip C.
Affiliation
  • Irwin KE; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD 21205-2196, USA.
  • Jasin P; Department of Neuroscience, Johns Hopkins Medicine, Baltimore, MD 21205-2196, USA.
  • Braunstein KE; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD 21205-2196, USA.
  • Sinha I; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD 21205-2196, USA.
  • Bowden KD; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD 21205-2196, USA.
  • Moghekar A; Department of Neuroscience, Johns Hopkins Medicine, Baltimore, MD 21205-2196, USA.
  • Oh ES; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD 21205-2196, USA.
  • Raitcheva D; Department of Neuroscience, Johns Hopkins Medicine, Baltimore, MD 21205-2196, USA.
  • Bartlett D; Department of Neurology, Johns Hopkins Medicine, Baltimore, MD 21205-2196, USA.
  • Berry JD; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD 21205-2196, USA.
  • Traynor B; Department of Medicine, Johns Hopkins Medicine, Baltimore, MD 21205-2196, USA.
  • Ling JP; Department of Psychiatry and Behavioral Sciences, Johns Hopkins Medicine, Baltimore, MD 21205-2196, USA.
  • Wong PC; Biogen, Cambridge, MA 02142, USA.
bioRxiv ; 2023 Jan 24.
Article in En | MEDLINE | ID: mdl-36789434

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: BioRxiv Year: 2023 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: BioRxiv Year: 2023 Document type: Article Affiliation country: United States Country of publication: United States