Ablation of Shank1 Protects against 6-OHDA-induced Cytotoxicity via PRDX3-mediated Inhibition of ER Stress in SN4741 Cells.

Xu, Ye-Ping; Zhang, Jing; Mei, Xue; Wu, Yan; Jiao, Wei; Wang, Yu-Hai; Zhang, Ai-Qin

Xu, Ye-Ping; Zhang, Jing; Mei, Xue; Wu, Yan; Jiao, Wei; Wang, Yu-Hai; Zhang, Ai-Qin.

Affiliation

Xu YP; Department of Nursing, Jinling Clinical Medical College, Nanjing Medical University, Nanjing, Jiangsu 210000, China.
Zhang J; Department of Neurosurgery, Wuxi Taihu Hospital, Wuxi Clinical College of Anhui Medical University, Wuxi, Jiangsu 214044, China.
Mei X; Department of Nursing, Wuxi Taihu Hospital, Wuxi Clinical College of Anhui Medical University, Wuxi, Jiangsu 214044, China.
Wu Y; Department of Nursing, Jinling Clinical Medical College, Nanjing Medical University, Nanjing, Jiangsu 210000, China.
Jiao W; Department of Nursing, Wuxi Taihu Hospital, Wuxi Clinical College of Anhui Medical University, Wuxi, Jiangsu 214044, China.
Wang YH; Department of Nursing, Wuxi Taihu Hospital, Wuxi Clinical College of Anhui Medical University, Wuxi, Jiangsu 214044, China.
Zhang AQ; Department of Neurosurgery, Wuxi Taihu Hospital, Wuxi Clinical College of Anhui Medical University, Wuxi, Jiangsu 214044, China.

CNS Neurol Disord Drug Targets ; 23(3): 402-410, 2024.

Article in En | MEDLINE | ID: mdl-36797610

Subject(s)

Parkinson Disease; Humans; Oxidopamine/toxicity; Apoptosis; Proteins; RNA, Small Interfering/metabolism; Peroxiredoxin III

Key words

6-OHDA; ER stress; PRDX3; Parkinson's disease; SN4741 cells; cytotoxicity.; shank1

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease Type of study: Prognostic_studies Limits: Humans Language: En Journal: CNS Neurol Disord Drug Targets Journal subject: NEUROLOGIA / TERAPIA POR MEDICAMENTOS Year: 2024 Document type: Article Affiliation country: China Country of publication: United Arab Emirates

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