Polycystic liver disease in golden hamsters.
J Comp Pathol
; 97(5): 615-8, 1987 Sep.
Article
in En
| MEDLINE
| ID: mdl-3680651
ABSTRACT
Seven cases of multiple hepatic cysts of varying sizes and shapes were recorded in a closed colony of golden hamsters. Ante-mortem examination failed to show any clinical signs except for abdominal enlargement in one hamster. Multiple, thin-walled cysts of varying sizes (0.25 to 3.0 cm) and shape were observed in the liver. The larger cysts protruded from the liver surfaces and contained a colourless, clear, serous fluid and caused pathological change in 5-60 per cent of the hepatic parenchyma. Microscopically, the cysts were uni- or multilocular and lined by low cuboidal or flattened epithelial cells. The hepatic parenchyma around cysts showed pressure atrophy, necrosis, engorged sinusoids or other blood vessels or even haemorrhages, mild to extensive fatty or vacuolar degenerative changes and occasionally proliferation of biliary ducts.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cricetinae
/
Mesocricetus
/
Cysts
/
Liver Diseases
Limits:
Animals
Language:
En
Journal:
J Comp Pathol
Year:
1987
Document type:
Article