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Investigation of the factors responsible for the low oral bioavailability of alizarin using a sensitive LC-MS/MS method: In vitro, in situ, and in vivo evaluations.
Seo, Seong-Wook; Han, Dong-Gyun; Baek, Young Mee; Park, Min Chul; Yoo, Jin-Wook; Jung, Yunjin; Maeng, Han-Joo; Myung, Heejoon; Yoon, In-Soo.
Affiliation
  • Seo SW; Department of Manufacturing Pharmacy, College of Pharmacy and Research Institute for Drug Development, Pusan National University, Busan, South Korea.
  • Han DG; Department of Manufacturing Pharmacy, College of Pharmacy and Research Institute for Drug Development, Pusan National University, Busan, South Korea.
  • Baek YM; Cultural Heritage Preservation Research Institute, Pusan National University, Busan, South Korea.
  • Park MC; College of Pharmacy and Inje Institute of Pharmaceutical Sciences and Research, Inje University, Gimhae, South Korea.
  • Yoo JW; Department of Manufacturing Pharmacy, College of Pharmacy and Research Institute for Drug Development, Pusan National University, Busan, South Korea.
  • Jung Y; Department of Manufacturing Pharmacy, College of Pharmacy and Research Institute for Drug Development, Pusan National University, Busan, South Korea.
  • Maeng HJ; Department of Pharmacy, College of Pharmacy, Gachon University, Incheon, South Korea.
  • Myung H; LyseNTech Co., Ltd., Seongnam-si, Gyunggi, South Korea.
  • Yoon IS; Department of Bioscience and Biotechnology, Hankuk University of Foreign Studies, Yongin-si, Gyunggi, South Korea.
Drug Dev Res ; 84(3): 579-591, 2023 05.
Article in En | MEDLINE | ID: mdl-36811607
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biological Products / Tandem Mass Spectrometry Type of study: Diagnostic_studies Limits: Animals / Humans Language: En Journal: Drug Dev Res Year: 2023 Document type: Article Affiliation country: South Korea Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biological Products / Tandem Mass Spectrometry Type of study: Diagnostic_studies Limits: Animals / Humans Language: En Journal: Drug Dev Res Year: 2023 Document type: Article Affiliation country: South Korea Country of publication: United States