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Optimization of 2,3-Dihydroquinazolinone-3-carboxamides as Antimalarials Targeting PfATP4.
Ashton, Trent D; Dans, Madeline G; Favuzza, Paola; Ngo, Anna; Lehane, Adele M; Zhang, Xinxin; Qiu, Deyun; Chandra Maity, Bikash; De, Nirupam; Schindler, Kyra A; Yeo, Tomas; Park, Heekuk; Uhlemann, Anne-Catrin; Churchyard, Alisje; Baum, Jake; Fidock, David A; Jarman, Kate E; Lowes, Kym N; Baud, Delphine; Brand, Stephen; Jackson, Paul F; Cowman, Alan F; Sleebs, Brad E.
Affiliation
  • Ashton TD; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.
  • Dans MG; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia.
  • Favuzza P; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.
  • Ngo A; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia.
  • Lehane AM; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.
  • Zhang X; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia.
  • Qiu D; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.
  • Chandra Maity B; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia.
  • De N; Research School of Biology, Australian National University, Canberra 2601, Australia.
  • Schindler KA; Research School of Biology, Australian National University, Canberra 2601, Australia.
  • Yeo T; Research School of Biology, Australian National University, Canberra 2601, Australia.
  • Park H; TCG Lifesciences Pvt. Ltd., Saltlake Sec-V, Kolkata 700091, West Bengal, India.
  • Uhlemann AC; TCG Lifesciences Pvt. Ltd., Saltlake Sec-V, Kolkata 700091, West Bengal, India.
  • Churchyard A; Department of Microbiology & Immunology, Columbia University, Irving Medical Center, New York, New York 10032, United States.
  • Baum J; Department of Microbiology & Immunology, Columbia University, Irving Medical Center, New York, New York 10032, United States.
  • Fidock DA; Department of Microbiology & Immunology, Columbia University, Irving Medical Center, New York, New York 10032, United States.
  • Jarman KE; Department of Microbiology & Immunology, Columbia University, Irving Medical Center, New York, New York 10032, United States.
  • Lowes KN; Department of Life Sciences, Imperial College London, South Kensington SW7 2AZ U.K.
  • Baud D; Department of Life Sciences, Imperial College London, South Kensington SW7 2AZ U.K.
  • Brand S; School of Biomedical Sciences, University of New South Wales, Sydney 2031, Australia.
  • Jackson PF; Department of Microbiology & Immunology, Columbia University, Irving Medical Center, New York, New York 10032, United States.
  • Cowman AF; Center for Malaria Therapeutics and Antimicrobial Resistance, Division of Infectious Diseases, Department of Medicine, Columbia University, Irving Medical Center, New York, New York 10032, United States.
  • Sleebs BE; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.
J Med Chem ; 66(5): 3540-3565, 2023 03 09.
Article in En | MEDLINE | ID: mdl-36812492
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Malaria, Falciparum / Malaria / Antimalarials Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2023 Document type: Article Affiliation country: Australia Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Malaria, Falciparum / Malaria / Antimalarials Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2023 Document type: Article Affiliation country: Australia Country of publication: United States