Gene and schizophrenia in the pregenome and postgenome-wide association studies era: a bibliometric analysis and network visualization.
Psychiatr Genet
; 33(2): 37-49, 2023 04 01.
Article
in En
| MEDLINE
| ID: mdl-36825838
ABSTRACT
This study aimed to perform a bibliometric analysis on genetic studies in schizophrenia in the pregenome-wide association studies (GWAS) and post-GWAS era. We searched the literature on genes and schizophrenia using the Scopus database. The documents increased with time, especially after the human genome project and International HapMap Project, with the highest citation in 2008. The top occurrence author keywords were discovered to be different in the pre-GWAS and post-GWAS eras, reflecting the progress of genetic studies connected to schizophrenia. Emerging keywords highlighted a trend towards an application of precision medicine, showing an interplay of environmental exposures as well as genetic factors in schizophrenia pathogenesis, progression, and response to therapy. In conclusion, the gene and schizophrenia literature has grown rapidly after the human genome project, and the temporal variation in the author keywords pattern reflects the trend of genetic studies related to schizophrenia in the pre-GWAS and post-GWAS era.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Schizophrenia
/
Genome-Wide Association Study
Type of study:
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
Psychiatr Genet
Journal subject:
GENETICA
/
PSIQUIATRIA
Year:
2023
Document type:
Article
Affiliation country:
Malaysia